RNA targeting with CRISPR–Cas13

RNA targeting with CRISPR–Cas13

RNA has important and diverse roles in biology, but molecular tools to manipulate and measure it are limited. For example, RNA interference1-3 can efficiently knockdown RNAs, but it is prone to off-target effects4, and visualizing RNAs typically relies on the introduction of exogenous tags5. Here we...

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Bibliographic Details
Main Authors: Essletzbichler, Patrick, Belanto, Joseph J., Verdine, Vanessa, Kellner, Max J., Voytas, Daniel F., Gootenberg, Jonathan S, Han, Shuo, Joung, Julia, Cox, David Benjamin Turitz, Regev, Aviv, Lander, Eric Steven, Zhang, Feng, Abudayyeh, Omar O., Ting, Alice Y.
Other Authors: Harvard University--MIT Division of Health Sciences and Technology
Format: Article
Published: Nature Publishing Group 2018
Online Access:http://hdl.handle.net/1721.1/116680
https://orcid.org/0000-0002-7979-3220
https://orcid.org/0000-0001-6656-5002
https://orcid.org/0000-0001-7626-4254
https://orcid.org/0000-0001-8567-2049
https://orcid.org/0000-0002-8277-5226
https://orcid.org/0000-0003-2782-2509

Internet

http://hdl.handle.net/1721.1/116680
https://orcid.org/0000-0002-7979-3220
https://orcid.org/0000-0001-6656-5002
https://orcid.org/0000-0001-7626-4254
https://orcid.org/0000-0001-8567-2049
https://orcid.org/0000-0002-8277-5226
https://orcid.org/0000-0003-2782-2509

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