De novo assembly of the Aedes aegypti genome using Hi-C yields chromosome-length scaffolds

De novo assembly of the Aedes aegypti genome using Hi-C yields chromosome-length scaffolds

The Zika outbreak, spread by the Aedes aegypti mosquito, highlights the need to create high-quality assemblies of large genomes in a rapid and cost-effective way. Here we combine Hi-C data with existing draft assemblies to generate chromosome-length scaffolds. We validate this method by assembling a...

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Bibliographic Details
Main Authors: Dudchenko, Olga, Batra, Sanjit S., Omer, Arina D., Hoeger, Marie, Durand, Neva C., Shamim, Muhammad S., Machol, Ido, Aiden, Aviva Presser, Aiden, Erez Lieberman, Nyquist, Sarah Kate, Lander, Eric Steven
Other Authors: Massachusetts Institute of Technology. Computational and Systems Biology Program
Format: Article
Published: American Association for the Advancement of Science (AAAS) 2018
Online Access:http://hdl.handle.net/1721.1/116720

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