Comprehensive molecular characterization of gastric adenocarcinoma

Comprehensive molecular characterization of gastric adenocarcinoma

Gastric cancer is a leading cause of cancer deaths, but analysis of its molecular and clinical characteristics has been complicated by histological and aetiological heterogeneity. Here we describe a comprehensive molecular evaluation of 295 primary gastric adenocarcinomas as part of The Cancer Genom...

Full description

Bibliographic Details
Main Authors:	Getz, Gad Asher, Sougnez, Carrie L, Jung, Joonil, Lander, Eric Steven, Lin, Pei, Voet, Douglas, Meyerson, Matthew L.
Other Authors:	Broad Institute of MIT and Harvard
Format:	Article
Published:	Nature Publishing Group 2018
Online Access:	http://hdl.handle.net/1721.1/116734

Similar Items

Comprehensive molecular characterization of clear cell renal cell carcinoma
by: Getz, Gad Asher, et al.
Published: (2018)

Comprehensive molecular profiling of lung adenocarcinoma
by: Lander, Eric Steven
Published: (2015)

Somatic retrotransposition in human cancer revealed by whole-genome and exome sequencing
by: Helman, Elena, et al.
Published: (2014)

Nkx2-1 Represses a Latent Gastric Differentiation Program in Lung Adenocarcinoma
by: Snyder, Eric L., et al.
Published: (2016)

Sensitive detection of somatic point mutations in impure and heterogeneous cancer samples
by: Cibulskis, Kristian, et al.
Published: (2014)

Comprehensive assessment of cancer missense mutation clustering in protein structures
by: Kamburov, Atanas, et al.
Published: (2018)

Comprehensive molecular characterization of human colon and rectal cancer
by: Lander, Eric Steven
Published: (2014)

Abundant copy-number loss of CYCLOPS and STOP genes in gastric adenocarcinoma
by: Cutcutache, Ioana, et al.
Published: (2016)

Mapping the Hallmarks of Lung Adenocarcinoma with Massively Parallel Sequencing
by: Hodis, Eran, et al.
Published: (2014)

Exome and whole-genome sequencing of esophageal adenocarcinoma identifies recurrent driver events and mutational complexity
by: Lander, Eric Steven
Published: (2014)

Paired exome analysis of Barrett's esophagus and adenocarcinoma
by: Stachler, Matthew D, et al.
Published: (2017)

Paired exome analysis of Barrett's esophagus and adenocarcinoma
by: Stachler, Matthew D, et al.
Published: (2016)

Integrated genomic analyses of ovarian carcinoma
by: Meyerson, Matthew L., et al.
Published: (2012)

Genomic sequencing of colorectal adenocarcinomas identifies a recurrent VTI1A-TCF7L2 fusion
by: Bass, Adam J., et al.
Published: (2014)

High-order chromatin architecture determines the landscape of chromosomal alterations in cancer
by: Fudenberg, Geoffrey, et al.
Published: (2012)

Helicobacter Species Identified in Captive Sooty Mangabeys (Cercocebus atys) with Metastatic Gastric Adenocarcinoma
by: Esmail, Michael Y., et al.
Published: (2020)

Characterization of HPV and host genome interactions in primary head and neck cancers
by: Freeman, Samuel Spenser Sharpe, et al.
Published: (2018)

Subtype-specific genomic alterations define new targets for soft tissue sarcoma therapy
by: Lander, Eric S., et al.
Published: (2012)

Somatic rearrangements across cancer reveal classes of samples with distinct patterns of DNA breakage and rearrangement-induced hypermutability
by: Drier, Yotam, et al.
Published: (2013)

GISTIC2.0 facilitates sensitive and confident localization of the targets of focal somatic copy-number alteration in human cancers
by: Mermel, Craig H., et al.
Published: (2011)

Protein expression of TGF-β, SMAD2 and RUNX3 in normal stomach, chronic gastritis and gastric adenocarcinoma
by: Ismail, Ahmad Zharif
Published: (2016)

Comprehensive Molecular Characterization of Pheochromocytoma and Paraganglioma
by: Fishbein, Lauren, et al.
Published: (2018)

Comprehensive genomic characterization of squamous cell lung cancers
by: Park, Peter J., et al.
Published: (2014)

Discovery and saturation analysis of cancer genes across 21 tumour types
by: Lawrence, Michael S., et al.
Published: (2015)

Activation of GATA binding protein 6 (GATA6) sustains oncogenic lineage-survival in esophageal adenocarcinoma
by: Lin, Lin, et al.
Published: (2012)

A comprehensive survey of genomic alterations in gastric cancer reveals systematic patterns of molecular exclusivity and co-occurrence among distinct therapeutic targets
by: Tao, Jiong, et al.
Published: (2013)

Colon cancer-derived oncogenic EGFR G724S mutant identified by whole genome sequence analysis is dependent on asymmetric dimerization and sensitive to cetuximab
by: Cho, Jeonghee, et al.
Published: (2014)

Molecular mechanics of cartilage : quantification of GAG electrostatic interactions via high-resolution force spectroscopy
by: Seog, Joonil, 1969-
Published: (2005)

PKM2 is not required for pancreatic ductal adenocarcinoma
by: Danai, Laura V, et al.
Published: (2018)

Proteomic studies on gastric cancer to understand the underlying molecular mechanisms of oncogenesis
by: Guo, Tiannan
Published: (2012)

Dysbiosis of the microbiome in gastric carcinogenesis
by: Castaño-Rodríguez, N., et al.
Published: (2017)

Integrative Genomics Viewer
by: Robinson, James T., et al.
Published: (2012)

Mouse Models of Gastric Cancer
by: Hayakawa, Yoku, et al.
Published: (2018)

Ingestible Electronics for High Quality Gastric Neural Recordings
by: Gierlach, Adam Matthew
Published: (2024)

CXCR4-expressing Mist1+ progenitors in the gastric antrum contribute to gastric cancer development
by: Sakitani, Kosuke, et al.
Published: (2018)

Suppression of Lung Adenocarcinoma Progression by Nkx2-1
by: Winslow, Monte Meier, et al.
Published: (2011)

Integrated cistromic and expression analysis of amplified NKX2-1 in lung adenocarcinoma identifies LMO3 as a functional transcriptional target
by: Watanabe, Hideo, et al.
Published: (2014)

Molecular characterization of doxorubicin resistance and cancer stem cells in a canine mammary adenocarcinoma cell line
by: Sahabi, Kabiru
Published: (2018)

Knowledge on gastric cancer, attitude on screening for gastric cancer and screening behavior of gastric cancer among out patients in Hospital Universiti Sains Malaysia
by: Saffai, Siti Norzietai
Published: (2023)

P53 expression in invasive pancreatic adenocarcinoma and precursor lesions
by: Norfadzilah, M.Y., et al.
Published: (2011)