IFNγ-Dependent Tissue-Immune Homeostasis Is Co-opted in the Tumor Microenvironment

IFNγ-Dependent Tissue-Immune Homeostasis Is Co-opted in the Tumor Microenvironment

Homeostatic programs balance immune protection and self-tolerance. Such mechanisms likely impact autoimmunity and tumor formation, respectively. How homeostasis is maintained and impacts tumor surveillance is unknown. Here, we find that different immune mononuclear phagocytes share a conserved stead...

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Bibliographic Details
Main Authors: Nirschl, Christopher J., Suárez-Fariñas, Mayte, Izar, Benjamin, Dannenfelser, Ruth, Tirosh, Itay, Liu, Yong, Zhu, Qian, Devi, K. Sanjana P., Chau, David, Rezaee, Melika, Kim, Tae-Gyun, Huang, Ruiqi, Fuentes-Duculan, Judilyn, Song-Zhao, George X., Gulati, Nicholas, Lowes, Michelle A., King, Sandra L., Quintana, Francisco J., Lee, Young-suk, Krueger, James G., Sarin, Kavita Y., Yoon, Charles H., Troyanskaya, Olga, Anandasabapathy, Niroshana, Prakadan, Sanjay, Carroll, Shaina Laufer, Regev, Aviv, Shalek, Alexander K, Garraway, Levi A.
Other Authors: Massachusetts Institute of Technology. Institute for Medical Engineering & Science
Format: Article
Published: Elsevier 2018
Online Access:http://hdl.handle.net/1721.1/116738
https://orcid.org/0000-0002-5621-8768
https://orcid.org/0000-0001-8567-2049
https://orcid.org/0000-0001-5670-8778

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