Cell-Type-Specific Alternative Splicing Governs Cell Fate in the Developing Cerebral Cortex

Cell-Type-Specific Alternative Splicing Governs Cell Fate in the Developing Cerebral Cortex

Alternative splicing is prevalent in the mammalian brain. To interrogate the functional role of alternative splicing in neural development, we analyzed purified neural progenitor cells (NPCs) and neurons from developing cerebral cortices, revealing hundreds of differentially spliced exons that prefe...

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Bibliographic Details
Main Authors: Zhang, Xiaochang, Chen, Ming Hui, Kodani, Andrew, Fan, Jean, Doan, Ryan, Ozawa, Manabu, Ma, Jacqueline, Yoshida, Nobuaki, Reiter, Jeremy F., Black, Douglas L., Kharchenko, Peter V., Walsh, Christopher A., Sharp, Phillip A., Wu, Xuebing, Ph. D. Massachusetts Institute of Technology
Other Authors: Massachusetts Institute of Technology. Computational and Systems Biology Program
Format: Article
Published: Elsevier 2018
Online Access:http://hdl.handle.net/1721.1/116859
https://orcid.org/0000-0003-0369-5269
https://orcid.org/0000-0003-1465-1691

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