Efficient kinetic experiments in continuous flow microreactors
Flow chemistry is an enabling technology that can offer an automated and robust approach for the generation of reaction kinetics data. Recent studies have taken advantage of transient flows to quickly generate concentration profiles with various online analytical tools. In this work, we demonstrate...
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| Format: | Article |
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Royal Society of Chemistry (RSC)
2018
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| Online Access: | http://hdl.handle.net/1721.1/116898 https://orcid.org/0000-0003-2346-4919 https://orcid.org/0000-0001-7192-580X |
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| author | Aroh, Kosi C. Jensen, Klavs F |
| author2 | Massachusetts Institute of Technology. Department of Chemical Engineering |
| author_facet | Massachusetts Institute of Technology. Department of Chemical Engineering Aroh, Kosi C. Jensen, Klavs F |
| author_sort | Aroh, Kosi C. |
| collection | MIT |
| description | Flow chemistry is an enabling technology that can offer an automated and robust approach for the generation of reaction kinetics data. Recent studies have taken advantage of transient flows to quickly generate concentration profiles with various online analytical tools. In this work, we demonstrate an improved method where temperature and flow are transient throughout the reaction. It was observed that only two orthogonal temperature ramp experiments under the same transient flow condition were sufficient to characterize a Paal-Knorr (one step bimolecular) reaction within our chosen reaction space. This method further shortens the time and decreases the materials needed to collect sufficient kinetic data and provides a framework with which more complex kinetic studies could be performed. |
| first_indexed | 2024-09-23T13:12:38Z |
| format | Article |
| id | mit-1721.1/116898 |
| institution | Massachusetts Institute of Technology |
| last_indexed | 2024-09-23T13:12:38Z |
| publishDate | 2018 |
| publisher | Royal Society of Chemistry (RSC) |
| record_format | dspace |
| spelling | mit-1721.1/1168982022-10-01T13:48:08Z Efficient kinetic experiments in continuous flow microreactors Aroh, Kosi C. Jensen, Klavs F Massachusetts Institute of Technology. Department of Chemical Engineering Aroh, Kosi C. Jensen, Klavs F Flow chemistry is an enabling technology that can offer an automated and robust approach for the generation of reaction kinetics data. Recent studies have taken advantage of transient flows to quickly generate concentration profiles with various online analytical tools. In this work, we demonstrate an improved method where temperature and flow are transient throughout the reaction. It was observed that only two orthogonal temperature ramp experiments under the same transient flow condition were sufficient to characterize a Paal-Knorr (one step bimolecular) reaction within our chosen reaction space. This method further shortens the time and decreases the materials needed to collect sufficient kinetic data and provides a framework with which more complex kinetic studies could be performed. 2018-07-11T15:51:43Z 2018-07-11T15:51:43Z 2018-01 2017-10 2018-07-11T14:28:02Z Article http://purl.org/eprint/type/JournalArticle 2058-9883 http://hdl.handle.net/1721.1/116898 Aroh, Kosi C. and Klavs F. Jensen. “Efficient Kinetic Experiments in Continuous Flow Microreactors.” Reaction Chemistry & Engineering 3, 1 (2018): 94–101 © 2018 Royal Society of Chemistry https://orcid.org/0000-0003-2346-4919 https://orcid.org/0000-0001-7192-580X http://dx.doi.org/10.1039/C7RE00163K Reaction Chemistry & Engineering Creative Commons Attribution 3.0 Unported license http://creativecommons.org/licenses/by/3.0/ application/pdf Royal Society of Chemistry (RSC) Royal Society of Chemistry |
| spellingShingle | Aroh, Kosi C. Jensen, Klavs F Efficient kinetic experiments in continuous flow microreactors |
| title | Efficient kinetic experiments in continuous flow microreactors |
| title_full | Efficient kinetic experiments in continuous flow microreactors |
| title_fullStr | Efficient kinetic experiments in continuous flow microreactors |
| title_full_unstemmed | Efficient kinetic experiments in continuous flow microreactors |
| title_short | Efficient kinetic experiments in continuous flow microreactors |
| title_sort | efficient kinetic experiments in continuous flow microreactors |
| url | http://hdl.handle.net/1721.1/116898 https://orcid.org/0000-0003-2346-4919 https://orcid.org/0000-0001-7192-580X |
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