The epigenetics of epithelial-mesenchymal plasticity in cancer
During the course of malignant cancer progression, neoplastic cells undergo dynamic and reversible transitions between multiple phenotypic states, the extremes of which are defined by the expression of epithelial and mesenchymal phenotypes. This plasticity is enabled by underlying shifts in epigenet...
Main Authors: | Tam, Wai Leong, Weinberg, Robert A |
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Other Authors: | Massachusetts Institute of Technology. Department of Biology |
Format: | Article |
Published: |
Nature Publishing Group
2018
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Online Access: | http://hdl.handle.net/1721.1/116944 https://orcid.org/0000-0002-0895-3557 |
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