An Integrin-Linked Machinery of Cytoskeletal Regulation that Enables Experimental Tumor Initiation and Metastatic Colonization
Recently extravasated metastatic cancer cells use the Rif/mDia2 actin-nucleating/polymerizing machinery in order to extend integrin β1-containing, filopodium-like protrusions (FLPs), which enable them to interact productively with the surrounding extracellular matrix; this process governs the initia...
Principais autores: | Shibue, Tsukasa, Brooks, Mary W., Weinberg, Robert A |
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Outros Autores: | Massachusetts Institute of Technology. Department of Biology |
Formato: | Artigo |
Publicado em: |
Elsevier
2018
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Acesso em linha: | http://hdl.handle.net/1721.1/116945 https://orcid.org/0000-0002-0895-3557 |
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