Epigenomic analysis detects aberrant super-enhancer DNA methylation in human cancer

Epigenomic analysis detects aberrant super-enhancer DNA methylation in human cancer

Background: One of the hallmarks of cancer is the disruption of gene expression patterns. Many molecular lesions contribute to this phenotype, and the importance of aberrant DNA methylation profiles is increasingly recognized. Much of the research effort in this area has examined proximal promoter r...

Full description

Bibliographic Details
Main Authors: Heyn, Holger, Vidal, Enrique, Ferreira, Humberto J., Vizoso, Miguel, Sayols, Sergi, Gomez, Antonio, Moran, Sebastian, Boque-Sastre, Raquel, Guil, Sonia, Martinez-Cardus, Anna, Royo, Romina, Sanchez-Mut, Jose V., Martinez, Ramon, Gut, Marta, Torrents, David, Orozco, Modesto, Gut, Ivo, Esteller, Manel, Lin, Charles Y., Young, Richard A.
Other Authors: Massachusetts Institute of Technology. Computational and Systems Biology Program
Format: Article
Published: Biomed Central Ltd 2018
Online Access:http://hdl.handle.net/1721.1/116983
https://orcid.org/0000-0001-8855-8647

Similar Items

Similar Items