CNS disease models with human pluripotent stem cells in the CRISPR age

CNS disease models with human pluripotent stem cells in the CRISPR age

In vitro differentiation of human pluripotent stem cells provides a systematic platform to investigate the physiological development and function of the human nervous system, as well as the etiology and consequence when these processes go awry. Recent development in three-dimensional (3D) organotypi...

Full description

Bibliographic Details
Main Authors:	Muffat, Julien, Lin, Yun, Jaenisch, Rudolf
Other Authors:	Massachusetts Institute of Technology. Department of Biology
Format:	Article
Language:	en_US
Published:	Elsevier 2018
Online Access:	http://hdl.handle.net/1721.1/117128

Similar Items

Technical Challenges in Using Human Induced Pluripotent Stem Cells to Model Disease
by: Saha, Krishanu, et al.
Published: (2015)

Efficient derivation of microglia-like cells from human pluripotent stem cells
by: Muffat, Julien, et al.
Published: (2017)

Human induced pluripotent stem cell-derived glial cells and neural progenitors display divergent responses to Zika and dengue infections
by: Muffat, Julien, et al.
Published: (2019)

Induced Pluripotent Stem Cells Meet Genome Editing
by: Hockemeyer, Dirk, et al.
Published: (2018)

Surface-engineered substrates for improved human pluripotent stem cell culture under fully defined conditions
by: Saha, Krishanu, et al.
Published: (2012)

Reprogramming of Human Peripheral Blood Cells to Induced Pluripotent Stem Cells
by: Staerk, Judith, et al.
Published: (2015)

Establishment of human pluripotent stem cell-derived pancreatic β-like cells in the mouse pancreas
by: Ma, Haiting, et al.
Published: (2018)

Human Naive Pluripotent Stem Cells Model X Chromosome Dampening and X Inactivation
by: Sahakyan, Anna, et al.
Published: (2018)

Functional analysis of CX3CR1 in human induced pluripotent stem (iPS) cell‐derived microglia‐like cells
by: Murai, Nobuhito, et al.
Published: (2021)

Modeling Alzheimer's disease with human induced pluripotent stem (iPS) cells
by: Mungenast, Alison, et al.
Published: (2017)

Genome-wide CRISPR screen for Zika virus resistance in human neural cells
by: Li, Yun, et al.
Published: (2020)

Chromatin Structure and Gene Expression Programs of Human Embryonic and Induced Pluripotent Stem Cells
by: Guenther, Matthew G., et al.
Published: (2015)

JIP2 haploinsufficiency contributes to neurodevelopmental abnormalities in human pluripotent stem cell–derived neural progenitors and cortical neurons
by: Roessler, Reinhard, et al.
Published: (2020)

Human Intestinal Tissue with Adult Stem Cell Properties Derived from Pluripotent Stem Cells
by: Forster, Ryan, et al.
Published: (2015)

Combinatorial Development of Biomaterials for Clonal Growth of Human Pluripotent Stem Cells
by: Mei, Ying, et al.
Published: (2012)

A plethora of human pluripotent stem cells
by: Liyang, Gao, et al.
Published: (2013)

Parkinson's Disease Patient-Derived Induced Pluripotent Stem Cells Free of Viral Reprogramming Factors
by: Soldner, Frank, et al.
Published: (2015)

7.342 Pluripotent Stem Cells and Genome Engineering for Modeling Human Diseases, Spring 2015
by: Cohen, Malkiel, et al.
Published: (2023)

Reversal of Phenotypic Abnormalities by CRISPR/Cas9-Mediated Gene Correction in Huntington Disease Patient-Derived Induced Pluripotent Stem Cells
by: Augustine, George James, et al.
Published: (2017)

Modelling genetic polycystic kidney disease using human pluripotent stem cell-derived kidney organoids
by: Liu, Meng
Published: (2023)

Epigenetic memory in induced pluripotent stem cells
by: Kim, K., et al.
Published: (2012)

SARS-CoV-2 infection of human pluripotent stem cell-derived liver organoids reveals potential mechanisms of liver pathology
by: Richards, Alexsia, et al.
Published: (2022)

Human embryonic stem cells with biological and epigenetic to those of mouse ESCs
by: Jaenisch, Rudolf, et al.
Published: (2011)

Defining essential enhancers for pluripotent stem cells using a features-oriented CRISPR-Cas9 screen
by: Wang, Hao Fei, et al.
Published: (2021)

Molecular Control of Induced Pluripotency
by: Theunissen, Thorold W., et al.
Published: (2016)

The promise of human induced pluripotent stem cells in dental research
by: Srijaya, Thekkeparambil Chandrabose, et al.
Published: (2012)

The effects of ageing on genomic stability, self-renewal and pluripotency of embryonic stem cells
by: Low, Kok Yao
Published: (2014)

Pluripotent stem cell-derived models of neurological diseases reveal early transcriptional heterogeneity
by: Sorek, Matan, et al.
Published: (2021)

Reprogramming of postnatal neurons into induced pluripotent stem cells by defined factors
by: Kim, Jongpil, et al.
Published: (2012)

Characterization of neural crest stem cells derived from human induced pluripotent stem cells.
by: Ling, Su Fung.
Published: (2009)

Dedifferentiation of hematopoietic stem cells into induced pluripotent stem cells
by: Monireh Soroush Noghabi
Published: (2011)

Roles for cell surface glycans in guiding human pluripotent stem cell fate
by: Mahbuba, Deena-Al
Published: (2022)

A roadmap for human liver differentiation from pluripotent stem cells
by: Ang, Lay Teng, et al.
Published: (2018)

Modeling hepatitis C virus infection using human induced pluripotent stem cells
by: Schwartz, Robert E., et al.
Published: (2014)

Human Vascular Tissue Models Formed from Human Induced Pluripotent Stem Cell Derived Endothelial Cells
by: Belair, David G., et al.
Published: (2015)

Pluripotent stem cell-derived hepatocyte-like cells
by: Schwartz, Robert E., et al.
Published: (2015)

Evaluation of minicircle-induced pluripotent stem cell
by: Daneshvar, Nasibeh
Published: (2014)

Deconstructing transcriptional heterogeneity in pluripotent stem cells
by: Kumar, Roshan M., et al.
Published: (2015)

Polymeric design of cell culture materials that guide the differentiation of human pluripotent stem cells
by: Higuchi, Akon, et al.
Published: (2017)

The design of a thermoresponsive surface for the continuous culture of human pluripotent stem cells
by: Sung, Tzu Cheng, et al.
Published: (2019)