Rehebbilitating Memory
Amnesia is a deficit of memory function that can result from trauma, stress, disease, drug use, or ageing. Though efforts are made to prevent and treat the various causes of amnesia, there remains no treatment for the symptom of memory loss itself. Because the defining feature of amnesia is an inabi...
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| Format: | Article |
| Language: | en_US |
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Nature Publishing Group
2018
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| Online Access: | http://hdl.handle.net/1721.1/117170 https://orcid.org/0000-0003-0121-8514 https://orcid.org/0000-0003-2839-8228 |
| _version_ | 1811093186041348096 |
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| author | Ryan, Tomas John Tonegawa, Susumu |
| author2 | Picower Institute for Learning and Memory |
| author_facet | Picower Institute for Learning and Memory Ryan, Tomas John Tonegawa, Susumu |
| author_sort | Ryan, Tomas John |
| collection | MIT |
| description | Amnesia is a deficit of memory function that can result from trauma, stress, disease, drug use, or ageing. Though efforts are made to prevent and treat the various causes of amnesia, there remains no treatment for the symptom of memory loss itself. Because the defining feature of amnesia is an inability recall memory, any given case may be due to the possibility that the
memory is damaged, or the alternative that it is present but irretrievable (Squire, 1982). Discriminating between these two scenarios would be of scientific value, because the neurobiology of memory formation is anchored in experimental amnesia. Pathological cases of amnesia that are due to retrieval deficits may in principal be treatable rather than merely preventable. Amnesia could be attributed to a retrieval deficit if the ostensible ‘lost’ memory could be evoked through brain stimulation. The challenge here is to identify exactly where in the brain a particular memory is stored. |
| first_indexed | 2024-09-23T15:41:02Z |
| format | Article |
| id | mit-1721.1/117170 |
| institution | Massachusetts Institute of Technology |
| language | en_US |
| last_indexed | 2024-09-23T15:41:02Z |
| publishDate | 2018 |
| publisher | Nature Publishing Group |
| record_format | dspace |
| spelling | mit-1721.1/1171702022-09-29T15:29:02Z Rehebbilitating Memory Ryan, Tomas John Tonegawa, Susumu Picower Institute for Learning and Memory RIKEN-MIT Center for Neural Circuit Genetics Tonegawa S Ryan, Tomas John Tonegawa, Susumu Amnesia is a deficit of memory function that can result from trauma, stress, disease, drug use, or ageing. Though efforts are made to prevent and treat the various causes of amnesia, there remains no treatment for the symptom of memory loss itself. Because the defining feature of amnesia is an inability recall memory, any given case may be due to the possibility that the memory is damaged, or the alternative that it is present but irretrievable (Squire, 1982). Discriminating between these two scenarios would be of scientific value, because the neurobiology of memory formation is anchored in experimental amnesia. Pathological cases of amnesia that are due to retrieval deficits may in principal be treatable rather than merely preventable. Amnesia could be attributed to a retrieval deficit if the ostensible ‘lost’ memory could be evoked through brain stimulation. The challenge here is to identify exactly where in the brain a particular memory is stored. JPB Foundation RIKEN Brain Science Institute 2018-07-27T18:11:54Z 2018-07-27T18:11:54Z 2015-12 Article http://purl.org/eprint/type/JournalArticle 0893-133X 1740-634X http://hdl.handle.net/1721.1/117170 Ryan, Tomás J., and Susumu Tonegawa. “Rehebbilitating Memory.” Neuropsychopharmacology, vol. 41, no. 1, Jan. 2016, pp. 370–71. https://orcid.org/0000-0003-0121-8514 https://orcid.org/0000-0003-2839-8228 en_US https://doi.org/10.1038/npp.2015.264 Neuropsychopharmacology Creative Commons Attribution-Noncommercial-Share Alike http://creativecommons.org/licenses/by-nc-sa/4.0/ application/pdf Nature Publishing Group Prof. Tonegawa via Courtney Crummett |
| spellingShingle | Ryan, Tomas John Tonegawa, Susumu Rehebbilitating Memory |
| title | Rehebbilitating Memory |
| title_full | Rehebbilitating Memory |
| title_fullStr | Rehebbilitating Memory |
| title_full_unstemmed | Rehebbilitating Memory |
| title_short | Rehebbilitating Memory |
| title_sort | rehebbilitating memory |
| url | http://hdl.handle.net/1721.1/117170 https://orcid.org/0000-0003-0121-8514 https://orcid.org/0000-0003-2839-8228 |
| work_keys_str_mv | AT ryantomasjohn rehebbilitatingmemory AT tonegawasusumu rehebbilitatingmemory |