Bacterial N-Glycosylation Efficiency is Dependent on the Structural Context of Target Sequons

Bacterial N-Glycosylation Efficiency is Dependent on the Structural Context of Target Sequons

Site selectivity of protein N-linked glycosylation is dependent on many factors, including accessibility of the modification site, amino acid composition of the glycosylation consensus sequence, and cellular localization of target proteins. Previous studies have shown that the bacterial oligosacchar...

Full description

Bibliographic Details
Main Authors:	Silverman, Julie, Imperiali, Barbara
Other Authors:	Massachusetts Institute of Technology. Department of Biology
Format:	Article
Language:	en_US
Published:	American Society for Biochemistry and Molecular Biology (ASBMB) 2018
Online Access:	http://hdl.handle.net/1721.1/117180 https://orcid.org/0000-0003-1432-0438 https://orcid.org/0000-0002-5749-7869

Similar Items

The Expanding Horizons of Asparagine-Linked Glycosylation
by: Larkin, Angelyn, et al.
Published: (2012)

Perturbing the folding energy landscape of the bacterial immunity protein Im7 by site-specific N-linked glycosylation
by: Chen, Mark, et al.
Published: (2011)

Development of a multicomponent kinetic assay of the early enzymes in the Campylobacter jejuni N-linked glycosylation pathway
by: Imperiali, Barbara, et al.
Published: (2017)

Genetic and molecular analyses reveal an evolutionary trajectory for glycan synthesis in a bacterial protein glycosylation system
by: Børud, Bente, et al.
Published: (2012)

Priming and processing glycosyltransferases in bacterial N-linked glycosylation pathways
by: Lukose, Vinita
Published: (2016)

Biochemical Characterization of the O-Linked Glycosylation Pathway in Neisseria gonorrhoeae Responsible for Biosynthesis of Protein Glycans Containing N,N '-Diacetylbacillosamine
by: Hartley, Meredith D., et al.
Published: (2012)

Bacterial carbohydrate diversity — a Brave New World
by: Imperiali, Barbara
Published: (2021)

Targeting Bacillosamine Biosynthesis in Bacterial Pathogens: Development of Inhibitors to a Bacterial Amino-Sugar Acetyltransferase from Campylobacter Jejuni
by: Ciulli, Alessio, et al.
Published: (2018)

Glycosylation: disease targets and therapy.
by: Zitzmann, N, et al.
Published: (2005)

Therapeutic targets for inhibitors of glycosylation.
by: Alonzi, D, et al.
Published: (2011)

Structure and Dynamics of N-Glycosylated Human Ribonuclease 1
by: Kilgore, Henry R, et al.
Published: (2021)

Investigation of asparagine-linked glycosylation in archaeal and bacterial systems
by: Larkin, Angelyn (Angelyn Kathryne)
Published: (2011)

Targeting glycosylation as a therapeutic approach.
by: Dwek, R, et al.
Published: (2002)

Optimized protocol for expression and purification of membrane-bound PglB, a bacterial oligosaccharyl transferase
by: Jaffee, Marcie Beth, et al.
Published: (2017)

Bacterial phosphoglycosyl transferases: initiators of glycan biosynthesis at the membrane interface
by: Lukose, Vinita, et al.
Published: (2020)

Biosynthesis of UDP-N,N′-diacetylbacillosamine in Acinetobacter baumannii: Biochemical characterization and correlation to existing pathways
by: Morrison, Michael James, et al.
Published: (2017)

Chemoenzymatic Assembly of Bacterial Glycoconjugates for Site-Specific Orthogonal Labeling
by: Lukose, Vinita, et al.
Published: (2017)

Thiol-reactive Derivatives of the Solvatochromic 4-N,N-Dimethylamino-1,8-naphthalimide Fluorophore: A Highly Sensitive Toolset for the Detection of Biomolecular Interactions
by: Loving, Galen S., et al.
Published: (2012)

Structural aspects of glycomes with a focus on N-glycosylation and glycoprotein folding.
by: Petrescu, A, et al.
Published: (2006)

GIFT domains: linking eukaryotic intraflagellar transport and glycosylation to bacterial gliding.
by: Beatson, S, et al.
Published: (2004)

Fundamental biochemistry of the early N-glycosylation pathway
by: Eddershaw, A
Published: (2024)

Uridine natural products: Challenging targets and inspiration for novel small molecule inhibitors
by: Arbour, Christine A, et al.
Published: (2021)

Uridine natural products: Challenging targets and inspiration for novel small molecule inhibitors
by: Arbour, Christine A, et al.
Published: (2021)

Consequences of the Endogenous N-Glycosylation of Human Ribonuclease 1
by: Ressler, Valerie T.(Valerie Terynn), et al.
Published: (2020)

Statistical analysis of the protein environment of N-glycosylation sites: implications for occupancy, structure, and folding.
by: Petrescu, A, et al.
Published: (2004)

Human complement factor I glycosylation: structural and functional characterisation of the N-linked oligosaccharides.
by: Tsiftsoglou, SA, et al.
Published: (2006)

Exploiting topological constraints to reveal buried sequence motifs in the membrane-bound N-linked oligosaccharyl transferases
by: Imperiali, Barbara, et al.
Published: (2012)

Structure of human endo-α-1,2-mannosidase (MANEA), an antiviral host-glycosylation target
by: Sobala, Ł, et al.
Published: (2020)

Biological investigation of glycosylated macromolecular structures
by: De Munari, S
Published: (2015)

Genetic determinants of genus-level glycan diversity in a bacterial protein glycosylation system
by: Hadjineophytou, C, et al.
Published: (2019)

Impact of infection on proteome-wide glycosylation revealed by distinct signatures for bacterial and viral pathogens
by: Willems, E, et al.
Published: (2023)

Conservation and Covariance in Small Bacterial Phosphoglycosyltransferases Identify the Functional Catalytic Core
by: Luo, Lingqi, et al.
Published: (2017)

Biochemical and biophysical investigations of N-linked glycosylation pathways in archaea
by: Chang, Michelle M. (Michelle Miran)
Published: (2015)

Identification of N-glycosylation changes in the CSF and serum in patients with schizophrenia.
by: Stanta, J, et al.
Published: (2010)

Synthesis of N-glycan oxazolines: donors for endohexosaminidase catalysed glycosylation.
by: Rising, T, et al.
Published: (2006)

Lipid bilayer nanodisc platform for investigating polyprenol-dependent enzyme interactions and activities
by: Hartley, Meredith D., et al.
Published: (2014)

Biochemical evidence for an alternate pathway in N-linked glycoprotein biosynthesis
by: Larkin, Angelyn, et al.
Published: (2015)

Glycoprotein structural genomics: solving the glycosylation problem.
by: Chang, V, et al.
Published: (2007)

Structural principles controlling HIV envelope glycosylation
by: Behrens, A, et al.
Published: (2017)

Structural and mechanistic themes in glycoconjugate biosynthesis at membrane interfaces
by: Allen, Karen N, et al.
Published: (2020)