Metabolic Teamwork in the Stem Cell Niche
Nearby cells can support stem cell differentiation, but the metabolic activities in stem cell niches are unknown. A recent study (Rodríguez-Colman et al., 2017) reveals a metabolic partnership in the intestinal stem cell niche: glycolysis in niche Paneth cells provides lactate to drive mitochondrial...
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| Format: | Article |
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Elsevier BV
2018
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| Online Access: | http://hdl.handle.net/1721.1/117191 https://orcid.org/0000-0002-7577-4612 |
| _version_ | 1826207924732559360 |
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| author | Roper, Jatin Yilmaz, Omer |
| author2 | Massachusetts Institute of Technology. Department of Biology |
| author_facet | Massachusetts Institute of Technology. Department of Biology Roper, Jatin Yilmaz, Omer |
| author_sort | Roper, Jatin |
| collection | MIT |
| description | Nearby cells can support stem cell differentiation, but the metabolic activities in stem cell niches are unknown. A recent study (Rodríguez-Colman et al., 2017) reveals a metabolic partnership in the intestinal stem cell niche: glycolysis in niche Paneth cells provides lactate to drive mitochondrial oxidative phosphorylation in intestinal stem cells. |
| first_indexed | 2024-09-23T13:57:07Z |
| format | Article |
| id | mit-1721.1/117191 |
| institution | Massachusetts Institute of Technology |
| last_indexed | 2024-09-23T13:57:07Z |
| publishDate | 2018 |
| publisher | Elsevier BV |
| record_format | dspace |
| spelling | mit-1721.1/1171912022-09-28T17:20:31Z Metabolic Teamwork in the Stem Cell Niche Roper, Jatin Yilmaz, Omer Massachusetts Institute of Technology. Department of Biology Koch Institute for Integrative Cancer Research at MIT Roper, Jatin Yilmaz, Omer Nearby cells can support stem cell differentiation, but the metabolic activities in stem cell niches are unknown. A recent study (Rodríguez-Colman et al., 2017) reveals a metabolic partnership in the intestinal stem cell niche: glycolysis in niche Paneth cells provides lactate to drive mitochondrial oxidative phosphorylation in intestinal stem cells. 2018-07-30T15:48:52Z 2018-07-30T15:48:52Z 2017-05 2018-07-13T16:07:43Z Article http://purl.org/eprint/type/JournalArticle 15504131 http://hdl.handle.net/1721.1/117191 Roper, Jatin, and Ömer H. Yilmaz. “Metabolic Teamwork in the Stem Cell Niche.” Cell Metabolism 25, no. 5 (May 2017): 993–994. https://orcid.org/0000-0002-7577-4612 http://dx.doi.org/10.1016/J.CMET.2017.04.019 Cell Metabolism Creative Commons Attribution-NonCommercial-NoDerivs License http://creativecommons.org/licenses/by-nc-nd/4.0/ application/pdf Elsevier BV PMC |
| spellingShingle | Roper, Jatin Yilmaz, Omer Metabolic Teamwork in the Stem Cell Niche |
| title | Metabolic Teamwork in the Stem Cell Niche |
| title_full | Metabolic Teamwork in the Stem Cell Niche |
| title_fullStr | Metabolic Teamwork in the Stem Cell Niche |
| title_full_unstemmed | Metabolic Teamwork in the Stem Cell Niche |
| title_short | Metabolic Teamwork in the Stem Cell Niche |
| title_sort | metabolic teamwork in the stem cell niche |
| url | http://hdl.handle.net/1721.1/117191 https://orcid.org/0000-0002-7577-4612 |
| work_keys_str_mv | AT roperjatin metabolicteamworkinthestemcellniche AT yilmazomer metabolicteamworkinthestemcellniche |