Short- and long-term effects of chromosome mis-segregation and aneuploidy
Dividing cells that experience chromosome mis-segregation generate aneuploid daughter cells, which contain an incorrect number of chromosomes. Although aneuploidy interferes with the proliferation of untransformed cells, it is also, paradoxically, a hallmark of cancer, a disease defined by increased...
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| Formato: | Artigo |
| Idioma: | en_US |
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Nature Publishing Group
2018
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| Acesso em linha: | http://hdl.handle.net/1721.1/117201 https://orcid.org/0000-0002-1501-6190 https://orcid.org/0000-0001-9837-0314 |