Scalable thin-layer membrane reactor for heterogeneous and homogeneous catalytic gas–liquid reactions
Catalytic gas–liquid reactions have potential as environmentally benign methods for organic synthesis, particularly hydrogenation and oxidation reactions. However, safety and scalability are concerns in the application of gas–liquid reactions. In this work, we develop and demonstrate a scalable, sus...
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| Format: | Article |
| Language: | en_US |
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Royal Society of Chemistry
2018
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| Online Access: | http://hdl.handle.net/1721.1/117488 https://orcid.org/0000-0002-7031-1133 https://orcid.org/0000-0001-7933-3155 https://orcid.org/0000-0001-7192-580X |
| _version_ | 1811079818984292352 |
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| author | Mo, Yiming Imbrogno, Joseph M Zhang, Haomiao Jensen, Klavs F |
| author2 | Massachusetts Institute of Technology. Department of Chemical Engineering |
| author_facet | Massachusetts Institute of Technology. Department of Chemical Engineering Mo, Yiming Imbrogno, Joseph M Zhang, Haomiao Jensen, Klavs F |
| author_sort | Mo, Yiming |
| collection | MIT |
| description | Catalytic gas–liquid reactions have potential as environmentally benign methods for organic synthesis, particularly hydrogenation and oxidation reactions. However, safety and scalability are concerns in the application of gas–liquid reactions. In this work, we develop and demonstrate a scalable, sustainable, and safe thin-layer membrane reactor for heterogeneous Pd-catalyzed hydrogenations and homogenous Cu(I)/TEMPO alcohol oxidations. The implementation of a Teflon amorphous fluoroplastic (AF) membrane and porous carbon cloth in the membrane reactor provides sufficient gas–liquid mass transfer to afford superior performance compared to conventional packed-bed or trickle-bed reactors. The membrane separates the gas from the liquid, which avoids the formation of explosive mixtures for oxygenation reactions and simplifies the two-phase hydrodynamics to facilitate scale-up by stacking modules, while significantly reducing gas consumption. In addition, 3-dimensional simulations deliver insights into the mass transfer and hydrodynamic behavior to inform optimal membrane reactor design and operation. |
| first_indexed | 2024-09-23T11:20:57Z |
| format | Article |
| id | mit-1721.1/117488 |
| institution | Massachusetts Institute of Technology |
| language | en_US |
| last_indexed | 2024-09-23T11:20:57Z |
| publishDate | 2018 |
| publisher | Royal Society of Chemistry |
| record_format | dspace |
| spelling | mit-1721.1/1174882022-10-01T03:00:41Z Scalable thin-layer membrane reactor for heterogeneous and homogeneous catalytic gas–liquid reactions Mo, Yiming Imbrogno, Joseph M Zhang, Haomiao Jensen, Klavs F Massachusetts Institute of Technology. Department of Chemical Engineering Mo, Yiming Imbrogno, Joseph M Zhang, Haomiao Jensen, Klavs F Catalytic gas–liquid reactions have potential as environmentally benign methods for organic synthesis, particularly hydrogenation and oxidation reactions. However, safety and scalability are concerns in the application of gas–liquid reactions. In this work, we develop and demonstrate a scalable, sustainable, and safe thin-layer membrane reactor for heterogeneous Pd-catalyzed hydrogenations and homogenous Cu(I)/TEMPO alcohol oxidations. The implementation of a Teflon amorphous fluoroplastic (AF) membrane and porous carbon cloth in the membrane reactor provides sufficient gas–liquid mass transfer to afford superior performance compared to conventional packed-bed or trickle-bed reactors. The membrane separates the gas from the liquid, which avoids the formation of explosive mixtures for oxygenation reactions and simplifies the two-phase hydrodynamics to facilitate scale-up by stacking modules, while significantly reducing gas consumption. In addition, 3-dimensional simulations deliver insights into the mass transfer and hydrodynamic behavior to inform optimal membrane reactor design and operation. 2018-08-22T18:56:46Z 2018-08-22T18:56:46Z 2018-07 2018-06 Article http://purl.org/eprint/type/JournalArticle 1463-9262 1463-9270 http://hdl.handle.net/1721.1/117488 Mo, Yiming et al. “Scalable Thin-Layer Membrane Reactor for Heterogeneous and Homogeneous Catalytic Gas–liquid Reactions.” Green Chemistry 20, 16 (2018): 3867–3874 © 2018 Royal Society of Chemistry https://orcid.org/0000-0002-7031-1133 https://orcid.org/0000-0001-7933-3155 https://orcid.org/0000-0001-7192-580X en_US http://dx.doi.org/10.1039/C8GC01917G Green Chemistry Creative Commons Attribution 3.0 Unported license http://creativecommons.org/licenses/by/3.0/ application/pdf Royal Society of Chemistry Royal Society of Chemistry |
| spellingShingle | Mo, Yiming Imbrogno, Joseph M Zhang, Haomiao Jensen, Klavs F Scalable thin-layer membrane reactor for heterogeneous and homogeneous catalytic gas–liquid reactions |
| title | Scalable thin-layer membrane reactor for heterogeneous and homogeneous catalytic gas–liquid reactions |
| title_full | Scalable thin-layer membrane reactor for heterogeneous and homogeneous catalytic gas–liquid reactions |
| title_fullStr | Scalable thin-layer membrane reactor for heterogeneous and homogeneous catalytic gas–liquid reactions |
| title_full_unstemmed | Scalable thin-layer membrane reactor for heterogeneous and homogeneous catalytic gas–liquid reactions |
| title_short | Scalable thin-layer membrane reactor for heterogeneous and homogeneous catalytic gas–liquid reactions |
| title_sort | scalable thin layer membrane reactor for heterogeneous and homogeneous catalytic gas liquid reactions |
| url | http://hdl.handle.net/1721.1/117488 https://orcid.org/0000-0002-7031-1133 https://orcid.org/0000-0001-7933-3155 https://orcid.org/0000-0001-7192-580X |
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