Chromatin Accessibility Impacts Transcriptional Reprogramming in Oocytes
Miyamoto et al. show genome-wide changes in chromatin accessibility during transcriptional reprogramming in oocytes using the frog nuclear transfer system. They demonstrate that donor cell chromatin states affect transcriptional reprogramming and changes in open chromatin during reprogramming are as...
| Main Authors: | , , , , , , , , , |
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| Format: | Article |
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Elsevier
2018
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| Online Access: | http://hdl.handle.net/1721.1/117522 https://orcid.org/0000-0002-3908-3048 https://orcid.org/0000-0002-4925-4699 |
| _version_ | 1826216462924120064 |
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| author | Miyamoto, Kei Allen, George E. Jullien, Jerome Otani, Tomoki Bradshaw, Charles R. Livesey, Frederick J. Gurdon, John B. Nguyen, Khoi Thien Kumar, Dinesh Kellis, Manolis |
| author2 | Massachusetts Institute of Technology. Computer Science and Artificial Intelligence Laboratory |
| author_facet | Massachusetts Institute of Technology. Computer Science and Artificial Intelligence Laboratory Miyamoto, Kei Allen, George E. Jullien, Jerome Otani, Tomoki Bradshaw, Charles R. Livesey, Frederick J. Gurdon, John B. Nguyen, Khoi Thien Kumar, Dinesh Kellis, Manolis |
| author_sort | Miyamoto, Kei |
| collection | MIT |
| description | Miyamoto et al. show genome-wide changes in chromatin accessibility during transcriptional reprogramming in oocytes using the frog nuclear transfer system. They demonstrate that donor cell chromatin states affect transcriptional reprogramming and changes in open chromatin during reprogramming are associated with specific transcription factors. Keywords:
open chromatin; transcriptional activation; reprogramming; nuclear transfer |
| first_indexed | 2024-09-23T16:47:46Z |
| format | Article |
| id | mit-1721.1/117522 |
| institution | Massachusetts Institute of Technology |
| last_indexed | 2024-09-23T16:47:46Z |
| publishDate | 2018 |
| publisher | Elsevier |
| record_format | dspace |
| spelling | mit-1721.1/1175222022-09-29T21:34:03Z Chromatin Accessibility Impacts Transcriptional Reprogramming in Oocytes Miyamoto, Kei Allen, George E. Jullien, Jerome Otani, Tomoki Bradshaw, Charles R. Livesey, Frederick J. Gurdon, John B. Nguyen, Khoi Thien Kumar, Dinesh Kellis, Manolis Massachusetts Institute of Technology. Computer Science and Artificial Intelligence Laboratory Massachusetts Institute of Technology. Department of Biological Engineering Nguyen, Khoi Thien Kumar, Dinesh Kellis, Manolis Miyamoto et al. show genome-wide changes in chromatin accessibility during transcriptional reprogramming in oocytes using the frog nuclear transfer system. They demonstrate that donor cell chromatin states affect transcriptional reprogramming and changes in open chromatin during reprogramming are associated with specific transcription factors. Keywords: open chromatin; transcriptional activation; reprogramming; nuclear transfer 2018-08-24T18:46:09Z 2018-08-24T18:46:09Z 2018-07 2018-03 2018-08-24T14:47:28Z Article http://purl.org/eprint/type/JournalArticle 2211-1247 http://hdl.handle.net/1721.1/117522 Miyamoto, Kei et al. “Chromatin Accessibility Impacts Transcriptional Reprogramming in Oocytes.” Cell Reports 24, 2 (July 2018): 304–311 https://orcid.org/0000-0002-3908-3048 https://orcid.org/0000-0002-4925-4699 http://dx.doi.org/10.1016/j.celrep.2018.06.030 Cell Reports Creative Commons Attribution 4.0 International License http://creativecommons.org/licenses/by/4.0/ application/pdf Elsevier Elsevier |
| spellingShingle | Miyamoto, Kei Allen, George E. Jullien, Jerome Otani, Tomoki Bradshaw, Charles R. Livesey, Frederick J. Gurdon, John B. Nguyen, Khoi Thien Kumar, Dinesh Kellis, Manolis Chromatin Accessibility Impacts Transcriptional Reprogramming in Oocytes |
| title | Chromatin Accessibility Impacts Transcriptional Reprogramming in Oocytes |
| title_full | Chromatin Accessibility Impacts Transcriptional Reprogramming in Oocytes |
| title_fullStr | Chromatin Accessibility Impacts Transcriptional Reprogramming in Oocytes |
| title_full_unstemmed | Chromatin Accessibility Impacts Transcriptional Reprogramming in Oocytes |
| title_short | Chromatin Accessibility Impacts Transcriptional Reprogramming in Oocytes |
| title_sort | chromatin accessibility impacts transcriptional reprogramming in oocytes |
| url | http://hdl.handle.net/1721.1/117522 https://orcid.org/0000-0002-3908-3048 https://orcid.org/0000-0002-4925-4699 |
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