A Blueprint for a Synthetic Genetic Feedback Controller to Reprogram Cell Fate
To artificially reprogram cell fate, experimentalists manipulate the gene regulatory networks (GRNs) that maintain a cell's phenotype. In practice, reprogramming is often performed by constant overexpression of specific transcription factors (TFs). This process can be unreliable and inefficient...
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| Format: | Article |
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Elsevier
2018
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| Online Access: | http://hdl.handle.net/1721.1/117580 https://orcid.org/0000-0001-6472-8576 https://orcid.org/0000-0002-1097-0401 https://orcid.org/0000-0002-5560-8246 |