Next generation high throughput DNA damage detection platform for genotoxic compound screening

Next generation high throughput DNA damage detection platform for genotoxic compound screening

Methods for quantifying DNA damage, as well as repair of that damage, in a high-throughput format are lacking. Single cell gel electrophoresis (SCGE; comet assay) is a widely-used method due to its technical simplicity and sensitivity, but the standard comet assay has limitations in reproducibility...

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Bibliographic Details
Main Authors: Sykora, Peter, Witt, Kristine L., Revanna, Pooja, Smith-Roe, Stephanie L., Dismukes, Jonathan, Lloyd, Donald G., Sobol, Robert W., Engelward, Bevin P
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering
Format: Article
Published: Nature Publishing Group 2018
Online Access:http://hdl.handle.net/1721.1/117598
https://orcid.org/0000-0003-4322-3573

Internet

http://hdl.handle.net/1721.1/117598
https://orcid.org/0000-0003-4322-3573

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