Early Detection of the Aflatoxin B₁ Mutational Fingerprint: A Diagnostic Tool for Liver Cancer

Using duplex-consensus sequencing technology, we recently identified the characteristic high-resolution mutational spectrum of the liver carcinogen aflatoxin B₁ in a mouse model, many months before aflatoxin-induced tumors are detectable. The diagnostic power of this spectrum is then demonstrated by...

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Bibliographic Details
Main Authors: Fedeles, Bogdan I, Chawanthayatham, Supawadee, Croy, Robert G, Wogan, Gerald N, Essigmann, John M
Other Authors: Massachusetts Institute of Technology. Center for Environmental Health Sciences
Format: Article
Published: Informa UK Limited 2018
Online Access:http://hdl.handle.net/1721.1/117661
https://orcid.org/0000-0001-5252-826X
https://orcid.org/0000-0003-0176-1920
https://orcid.org/0000-0003-0771-9889
https://orcid.org/0000-0002-2196-5691