Early Detection of the Aflatoxin B₁ Mutational Fingerprint: A Diagnostic Tool for Liver Cancer
Using duplex-consensus sequencing technology, we recently identified the characteristic high-resolution mutational spectrum of the liver carcinogen aflatoxin B₁ in a mouse model, many months before aflatoxin-induced tumors are detectable. The diagnostic power of this spectrum is then demonstrated by...
Main Authors: | Fedeles, Bogdan I, Chawanthayatham, Supawadee, Croy, Robert G, Wogan, Gerald N, Essigmann, John M |
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Other Authors: | Massachusetts Institute of Technology. Center for Environmental Health Sciences |
Format: | Article |
Published: |
Informa UK Limited
2018
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Online Access: | http://hdl.handle.net/1721.1/117661 https://orcid.org/0000-0001-5252-826X https://orcid.org/0000-0003-0176-1920 https://orcid.org/0000-0003-0771-9889 https://orcid.org/0000-0002-2196-5691 |
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