Inflammatory but not mitogenic contexts prime synovial fibroblasts for compensatory signaling responses to p38 inhibition

Rheumatoid arthritis (RA) is a chronic inflammatory disorder that causes joint pain, swelling, and loss of function. Development of effective new drugs has proven challenging in part because of the complexities and interconnected nature of intracellular signaling networks that complicate the effects...

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书目详细资料
Main Authors: Jenney, Anne P., Sorger, Peter K., Jones II, Douglas S., Joughin, Brian Alan, Lauffenburger, Douglas A
其他作者: Massachusetts Institute of Technology. Department of Biological Engineering
格式: 文件
出版: American Association for the Advancement of Science 2018
在线阅读:http://hdl.handle.net/1721.1/117688
https://orcid.org/0000-0003-1022-9450
https://orcid.org/0000-0002-0050-989X