Tyro3 carboxyl terminal region confers stability and contains the autophosphorylation sites
Tyro3, a member of TAM receptor tyrosine kinase family has been suggested to be autophosphorylated upon activation. In the current study we mapped the autophosphorylation sites of murine Tyro3 to tyrosine 723 and 756, with K540 being required for its kinase activity. Knockdown of Axl significantly d...
Main Authors: | Shao, Hanshuang, Wells, Alan, Lauffenburger, Douglas A |
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Other Authors: | Massachusetts Institute of Technology. Department of Biological Engineering |
Format: | Article |
Published: |
Elsevier
2018
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Online Access: | http://hdl.handle.net/1721.1/117689 https://orcid.org/0000-0002-0050-989X |
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