Loss of spatial organization and destruction of the pericellular matrix in early osteoarthritis in vivo and in a novel in vitro methodology

Loss of spatial organization and destruction of the pericellular matrix in early osteoarthritis in vivo and in a novel in vitro methodology

Objectives: Current repair procedures for articular cartilage (AC) cannot restore the tissue's original form and function because neither changes in its architectural blueprint throughout life nor the respective biological understanding is fully available. We asked whether two unique elements o...

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Bibliographic Details
Main Authors: Rothdiener, M., Bast, S., Uynuk-Ool, T., Zouhair, S., Ochs, B.G., De Zwart, P., Stoeckle, U., Aicher, W.K., Hart, M.L., Shiozawa, T., Schenke-Layland, K., Venkatesan, J.K., Cucchiarini, M., Madry, H., Kurz, B., Felka, Tino, Grodzinsky, Alan J, Rolauffs, Bernd G
Other Authors: Harvard University--MIT Division of Health Sciences and Technology
Format: Article
Published: Elsevier BV 2018
Online Access:http://hdl.handle.net/1721.1/117772
https://orcid.org/0000-0002-4942-3456

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