CRISPR-mediated interrogation of small cell lung cancer

CRISPR-mediated interrogation of small cell lung cancer

Thesis: Ph. D., Massachusetts Institute of Technology, Department of Biology, 2018.

Bibliographic Details
Main Author:	Ng, Sheng Rong
Other Authors:	Tyler Jacks.
Format:	Thesis
Language:	eng
Published:	Massachusetts Institute of Technology 2018
Subjects:	Biology.
Online Access:	http://hdl.handle.net/1721.1/117782

Similar Items

CRISPR-mediated modeling and functional validation of candidate tumor suppressor genes in small cell lung cancer
by: Ng, Sheng Rong, et al.
Published: (2020)

Investigating the initiation and progression of small cell lung cancer
by: Brauneis, Alison Dooley
Published: (2011)

Using CRISPR/Cas9 approaches to interrogate and delineate viral gene expression programmes
by: Oh, Season Jing Wen
Published: (2023)

Selectins Mediate Small Cell Lung Cancer Systemic Metastasis
by: Heidemann, Franziska, et al.
Published: (2014)

Interrogation of CRISPR-Cas targeting specificity for mammalian genome engineering
by: Scott, David (David Arthur)
Published: (2018)

Interrogating the lungs through wearable fabric electronics
by: Fung, Johnny(Johnny Z.)
Published: (2020)

Investigating functions of tumor-infiltrating natural killer cells in genetically-engineered mouse models of non-small cell lung cancer
by: Schmidt, Leah Marie
Published: (2016)

Constructing and deconstructing cancer using CRISPR-Cas9
by: Sánchez-Rivera, Francisco J. (Francisco Javier)
Published: (2016)

In vivo interrogation of gene function in the mammalian brain using CRISPR-Cas9
by: Swiech, Lukasz, et al.
Published: (2016)

Theranostics application of tumor-initiating cell probe TiY in non-small cell lung cancer
by: Lee, Yong-An, et al.
Published: (2023)

Functional miRNA regulation of metastatic genes promotes tumor cell dissemination in non-small cell and small cell lung carcinomas
by: Blat, Irene Catherine
Published: (2013)

Interrogation of functional miRNA–target interactions by CRISPR/Cas9 genome engineering
by: Michaels, YS, et al.
Published: (2017)

An organoid platform to study alveolar stem cells in lung generation and cancer
by: Naranjo, Santiago(Santiago Jose)
Published: (2021)

Optimization of the CRISPR/Cas9 system for excision of genomic regions in human cancer cell cultures
by: Tng, Jia Qi
Published: (2016)

Comparative transcriptomics unravels prodigiosin's potential cancer-specific activity between human small airway epithelial cells and lung adenocarcinoma cells
by: Davient, Bala, et al.
Published: (2018)

Mouse models of lung cancer : understanding the molecular and cellular basis of lung tumorigenesis
by: Jackson, Erica L. (Erica Lynn), 1973-
Published: (2006)

Optimising CRISPR for targeting of primary haematopoietic stem cells
by: Field, L
Published: (2021)

Effect of beta-sitosterol and plant extracts on skin cancer cells
by: Lau, Rong Sheng
Published: (2015)

CRISPR-mediated direct mutation of cancer genes in the mouse liver
by: Xue, Wen, et al.
Published: (2015)

Antigens of small-cell lung cancer. First International Workshop.
by: Souhami, R, et al.
Published: (1987)

Paraneoplastic neurological autoimmunity and survival in small-cell lung cancer.
by: Maddison, P, et al.
Published: (2008)

BMI1 is a context-dependent tumor suppressor that is a barrier to dedifferentiation in non-small cell lung adenocarcinoma
by: Neupane, Rachit.
Published: (2019)

Integrated genetic and pharmacologic interrogation of rare cancers
by: Jonas, Oliver H., et al.
Published: (2016)

HNMT Upregulation Induces Cancer Stem Cell Formation and Confers Protection against Oxidative Stress through Interaction with HER2 in Non-Small-Cell Lung Cancer
by: Kuo, Kuang-Tai, et al.
Published: (2022)

Functionalizing novel modulators of lung cancer
by: Lee, Yi Fei
Published: (2022)

CRISPR/Cas9-system mediated deletion of the Neurofibromin 1 tumour suppressor gene in human gliomas
by: Siti Farah Fadhlullah
Published: (2015)

Qualitative and quantitative approaches to modelling tyrosine kinase inhibitor treatment and resistance in non-small cell lung cancer
by: Carrick Smith, EJ
Published: (2021)

Interrogation of Changes in Cell State during Tumor Evolution of a Genetically Engineered Mouse Model of Lung Adenocarcinoma
by: Cruz, Amanda Margarita
Published: (2022)

Computationally interrogating enzyme electrochemistry for rational mutation of metalloproteins
by: Lloyd-Laney, H
Published: (2021)

Nuclear Factor I/B is an Oncogene in Small Cell Lung Cancer
by: Dooley, Alison L., et al.
Published: (2011)

Small RNA combination therapy for lung cancer
by: Tammela, Tuomas, et al.
Published: (2015)

Review of hypofractionated small volume radiotherapy for early-stage non-small cell lung cancer.
by: Brock, J, et al.
Published: (2008)

Interrogation of torture.
by: Hoo, Tiang Boon.
Published: (2010)

Engineering small molecule-mediated communication between light-activatable synthetic cells and bacterial cells
by: Smith, J
Published: (2022)

Methods to interrogate cells and their interactions with single-cell resolution
by: Genshaft, Alexander S.
Published: (2020)

Agrobacterium-mediated transformation by using immerse and agroinfiltration method for genome editing of orchids with CRISPR/Cas9
by: Subchan, A. N., et al.
Published: (2022)

Targeting inflammation in non-small cell lung cancer through drug repurposing
by: Rajasegaran, Thiviyadarshini, et al.
Published: (2023)

Gene expression signature for angiogenic and nonangiogenic non-small-cell lung cancer.
by: Hu, J, et al.
Published: (2005)

Chapter 1 The first international workshop on small cell lung cancer antigens
by: Souhami, R, et al.
Published: (1988)

Prediction model for small-cell lung cancer in the Lambert-Eaton myasthenic syndrome
by: Titulaer, M, et al.
Published: (2010)