OptMAVEn-2.0: De novo Design of Variable Antibody Regions Against Targeted Antigen Epitopes
Monoclonal antibodies are becoming increasingly important therapeutic agents for the treatment of cancers, infectious diseases, and autoimmune disorders. However, laboratory-based methods of developing therapeutic monoclonal antibodies (e.g., immunized mice, hybridomas, and phage display) are time-c...
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| Format: | Article |
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Multidisciplinary Digital Publishing Institute (MDPI)
2018
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| Online Access: | http://hdl.handle.net/1721.1/118300 https://orcid.org/0000-0001-8182-7402 |