Efficient and tumor-specific knockdown of MTDH gene attenuates paclitaxel resistance of breast cancer cells both in vivo and in vitro

Efficient and tumor-specific knockdown of MTDH gene attenuates paclitaxel resistance of breast cancer cells both in vivo and in vitro

Background Drug resistance of paclitaxel (TAX), the first-line chemotherapy drug for breast cancer, was reported to develop in 90% of patients with breast cancer, especially metastatic breast cancer. Investigating the mechanism of TAX resistance of breast cancer cells and developing...

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Bibliographic Details
Main Authors: Yang, Liu, Tian, Yanhua, Leong, Wei Sun, Song, Heng, Yang, Wei, Wang, Meiqi, Wang, Xinle, Kong, Jing, Shan, Baoen, Song, Zhengchuan
Other Authors: Massachusetts Institute of Technology. Department of Electrical Engineering and Computer Science
Format: Article
Language:English
Published: BioMed Central 2018
Online Access:http://hdl.handle.net/1721.1/118308
https://orcid.org/0000-0001-8131-2468
https://orcid.org/0000-0003-0551-1208

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