Crystallographic capture of a radical S-adenosylmethionine enzyme in the act of modifying tRNA
RlmN is a dual-specificity RNA methylase that modifies C2 of adenosine 2503 (A2503) in 23S rRNA and C2 of adenosine 37 (A37) in several Escherichia coli transfer RNAs (tRNAs). A related methylase, Cfr, modifies C8 of A2503 via a similar mechanism, conferring resistance to multiple classes of antibio...
| Main Authors: | , , , |
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| Other Authors: | |
| Format: | Article |
| Published: |
American Association for the Advancement of Science (AAAS)
2018
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| Online Access: | http://hdl.handle.net/1721.1/118446 |