A roadmap for gene drives: using institutional analysis and development to frame research needs and governance in a systems context
The deployment of gene drives is emerging as an alternative for protecting endangered species, controlling agricultural pests, and reducing vector-borne diseases. This paper reports on a workshop held in February 2016 to explore the complex intersection of political, economic, ethical, and ecologica...
| Main Authors: | , , , , , , , , , , |
|---|---|
| Other Authors: | |
| Format: | Article |
| Published: |
Informa UK Limited
2018
|
| Online Access: | http://hdl.handle.net/1721.1/118652 https://orcid.org/0000-0002-9811-8415 |
| _version_ | 1826198462316675072 |
|---|---|
| author | Kuzma, J. Gould, F. Brown, Z. Collins, J. Delborne, J. Frow, E. Guston, D. Leitschuh, C. Stauffer, S. Esvelt, Kevin Michael Oye, Kenneth A |
| author2 | Massachusetts Institute of Technology. Department of Political Science |
| author_facet | Massachusetts Institute of Technology. Department of Political Science Kuzma, J. Gould, F. Brown, Z. Collins, J. Delborne, J. Frow, E. Guston, D. Leitschuh, C. Stauffer, S. Esvelt, Kevin Michael Oye, Kenneth A |
| author_sort | Kuzma, J. |
| collection | MIT |
| description | The deployment of gene drives is emerging as an alternative for protecting endangered species, controlling agricultural pests, and reducing vector-borne diseases. This paper reports on a workshop held in February 2016 to explore the complex intersection of political, economic, ethical, and ecological risk issues associated with gene drives. Workshop participants were encouraged to use systems thinking and mapping to describe the connections among social, policy, economic, and ecological variables as they intersect within governance systems. In this paper, we analyze the workshop transcripts and maps using the Institutional Analysis and Development (IAD) framework to categorize variables associated with gene drive governance and account for the complexities of socio-ecological systems. We discuss how the IAD framework can be used in the future to test hypotheses about how features of governance systems might lead to certain outcomes and inform the design of research programs, public engagement, and anticipatory governance of gene drives. Keywords: Gene drive; governance; risk; systems; IAD; genetic engineering |
| first_indexed | 2024-09-23T11:05:20Z |
| format | Article |
| id | mit-1721.1/118652 |
| institution | Massachusetts Institute of Technology |
| last_indexed | 2024-09-23T11:05:20Z |
| publishDate | 2018 |
| publisher | Informa UK Limited |
| record_format | dspace |
| spelling | mit-1721.1/1186522022-10-01T01:06:38Z A roadmap for gene drives: using institutional analysis and development to frame research needs and governance in a systems context Kuzma, J. Gould, F. Brown, Z. Collins, J. Delborne, J. Frow, E. Guston, D. Leitschuh, C. Stauffer, S. Esvelt, Kevin Michael Oye, Kenneth A Massachusetts Institute of Technology. Department of Political Science Massachusetts Institute of Technology. Institute for Data, Systems, and Society Program in Media Arts and Sciences (Massachusetts Institute of Technology) Esvelt, Kevin Michael Oye, Kenneth A The deployment of gene drives is emerging as an alternative for protecting endangered species, controlling agricultural pests, and reducing vector-borne diseases. This paper reports on a workshop held in February 2016 to explore the complex intersection of political, economic, ethical, and ecological risk issues associated with gene drives. Workshop participants were encouraged to use systems thinking and mapping to describe the connections among social, policy, economic, and ecological variables as they intersect within governance systems. In this paper, we analyze the workshop transcripts and maps using the Institutional Analysis and Development (IAD) framework to categorize variables associated with gene drive governance and account for the complexities of socio-ecological systems. We discuss how the IAD framework can be used in the future to test hypotheses about how features of governance systems might lead to certain outcomes and inform the design of research programs, public engagement, and anticipatory governance of gene drives. Keywords: Gene drive; governance; risk; systems; IAD; genetic engineering 2018-10-22T17:22:13Z 2018-10-22T17:22:13Z 2017-12 2017-06 2018-10-18T14:18:47Z Article http://purl.org/eprint/type/JournalArticle 2329-9460 2329-9037 http://hdl.handle.net/1721.1/118652 Kuzma, J., et al. “A Roadmap for Gene Drives: Using Institutional Analysis and Development to Frame Research Needs and Governance in a Systems Context.” Journal of Responsible Innovation, vol. 5, no. sup1, Jan. 2018, pp. S13–39. © 2017 The Authors https://orcid.org/0000-0002-9811-8415 http://dx.doi.org/10.1080/23299460.2017.1410344 Journal of Responsible Innovation Creative Commons Attribution-NonCommercial-NoDerivs License http://creativecommons.org/licenses/by-nc-nd/4.0/ application/pdf Informa UK Limited Taylor & Francis |
| spellingShingle | Kuzma, J. Gould, F. Brown, Z. Collins, J. Delborne, J. Frow, E. Guston, D. Leitschuh, C. Stauffer, S. Esvelt, Kevin Michael Oye, Kenneth A A roadmap for gene drives: using institutional analysis and development to frame research needs and governance in a systems context |
| title | A roadmap for gene drives: using institutional analysis and development to frame research needs and governance in a systems context |
| title_full | A roadmap for gene drives: using institutional analysis and development to frame research needs and governance in a systems context |
| title_fullStr | A roadmap for gene drives: using institutional analysis and development to frame research needs and governance in a systems context |
| title_full_unstemmed | A roadmap for gene drives: using institutional analysis and development to frame research needs and governance in a systems context |
| title_short | A roadmap for gene drives: using institutional analysis and development to frame research needs and governance in a systems context |
| title_sort | roadmap for gene drives using institutional analysis and development to frame research needs and governance in a systems context |
| url | http://hdl.handle.net/1721.1/118652 https://orcid.org/0000-0002-9811-8415 |
| work_keys_str_mv | AT kuzmaj aroadmapforgenedrivesusinginstitutionalanalysisanddevelopmenttoframeresearchneedsandgovernanceinasystemscontext AT gouldf aroadmapforgenedrivesusinginstitutionalanalysisanddevelopmenttoframeresearchneedsandgovernanceinasystemscontext AT brownz aroadmapforgenedrivesusinginstitutionalanalysisanddevelopmenttoframeresearchneedsandgovernanceinasystemscontext AT collinsj aroadmapforgenedrivesusinginstitutionalanalysisanddevelopmenttoframeresearchneedsandgovernanceinasystemscontext AT delbornej aroadmapforgenedrivesusinginstitutionalanalysisanddevelopmenttoframeresearchneedsandgovernanceinasystemscontext AT frowe aroadmapforgenedrivesusinginstitutionalanalysisanddevelopmenttoframeresearchneedsandgovernanceinasystemscontext AT gustond aroadmapforgenedrivesusinginstitutionalanalysisanddevelopmenttoframeresearchneedsandgovernanceinasystemscontext AT leitschuhc aroadmapforgenedrivesusinginstitutionalanalysisanddevelopmenttoframeresearchneedsandgovernanceinasystemscontext AT stauffers aroadmapforgenedrivesusinginstitutionalanalysisanddevelopmenttoframeresearchneedsandgovernanceinasystemscontext AT esveltkevinmichael aroadmapforgenedrivesusinginstitutionalanalysisanddevelopmenttoframeresearchneedsandgovernanceinasystemscontext AT oyekennetha aroadmapforgenedrivesusinginstitutionalanalysisanddevelopmenttoframeresearchneedsandgovernanceinasystemscontext AT kuzmaj roadmapforgenedrivesusinginstitutionalanalysisanddevelopmenttoframeresearchneedsandgovernanceinasystemscontext AT gouldf roadmapforgenedrivesusinginstitutionalanalysisanddevelopmenttoframeresearchneedsandgovernanceinasystemscontext AT brownz roadmapforgenedrivesusinginstitutionalanalysisanddevelopmenttoframeresearchneedsandgovernanceinasystemscontext AT collinsj roadmapforgenedrivesusinginstitutionalanalysisanddevelopmenttoframeresearchneedsandgovernanceinasystemscontext AT delbornej roadmapforgenedrivesusinginstitutionalanalysisanddevelopmenttoframeresearchneedsandgovernanceinasystemscontext AT frowe roadmapforgenedrivesusinginstitutionalanalysisanddevelopmenttoframeresearchneedsandgovernanceinasystemscontext AT gustond roadmapforgenedrivesusinginstitutionalanalysisanddevelopmenttoframeresearchneedsandgovernanceinasystemscontext AT leitschuhc roadmapforgenedrivesusinginstitutionalanalysisanddevelopmenttoframeresearchneedsandgovernanceinasystemscontext AT stauffers roadmapforgenedrivesusinginstitutionalanalysisanddevelopmenttoframeresearchneedsandgovernanceinasystemscontext AT esveltkevinmichael roadmapforgenedrivesusinginstitutionalanalysisanddevelopmenttoframeresearchneedsandgovernanceinasystemscontext AT oyekennetha roadmapforgenedrivesusinginstitutionalanalysisanddevelopmenttoframeresearchneedsandgovernanceinasystemscontext |