High-Frequency, Functional HIV-Specific T-Follicular Helper and Regulatory Cells Are Present Within Germinal Centers in Children but Not Adults

High-Frequency, Functional HIV-Specific T-Follicular Helper and Regulatory Cells Are Present Within Germinal Centers in Children but Not Adults

Broadly neutralizing antibodies (bnAbs) against HIV-1 are an effective means of preventing transmission. To better understand the mechanisms by which HIV-specific bnAbs naturally develop, we investigated blood and lymphoid tissue in pediatric infection, since potent bnAbs develop with greater freque...

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Bibliographic Details
Main Authors: Roider, Julia, Maehara, Takashi, Ngoepe, Abigail, Ramsuran, Duran, Muenchhoff, Maximilian, Adland, Emily, Jooste, Pieter, Karim, Farina, Kuhn, Warren, Ndung'u, Thumbi, Morris, Lynn, Moore, Penny L., Kløverpris, Henrik, Goulder, Philip, Leslie, Alasdair, Aicher, Toby Paul, Kazer, Samuel Weisgurt, Shalek, Alexander K, Pillai, Shiv
Other Authors: Institute for Medical Engineering and Science
Format: Article
Published: Frontiers Research Foundation 2018
Online Access:http://hdl.handle.net/1721.1/118748
https://orcid.org/0000-0002-7380-9594
https://orcid.org/0000-0001-5670-8778

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