Bioengineered Fascicle-Like Skeletal Muscle Tissue Constructs
Tissue engineered skeletal muscle constructs have and will continue to be valuable in treating, and testing various muscle injuries and diseases. However a significant drawback to numerous methods of producing 3D skeletal muscle constructs grown in vitro is that muscle cell density as a fraction of...
| Main Authors: | , , |
|---|---|
| Other Authors: | |
| Format: | Article |
| Published: |
ASME International
2018
|
| Online Access: | http://hdl.handle.net/1721.1/118781 https://orcid.org/0000-0003-3155-6223 |
| _version_ | 1826214604004392960 |
|---|---|
| author | Neal, Devin M Sakar, Mahmut Selman Asada, Haruhiko |
| author2 | Massachusetts Institute of Technology. Department of Mechanical Engineering |
| author_facet | Massachusetts Institute of Technology. Department of Mechanical Engineering Neal, Devin M Sakar, Mahmut Selman Asada, Haruhiko |
| author_sort | Neal, Devin M |
| collection | MIT |
| description | Tissue engineered skeletal muscle constructs have and will continue to be valuable in treating, and testing various muscle injuries and diseases. However a significant drawback to numerous methods of producing 3D skeletal muscle constructs grown in vitro is that muscle cell density as a fraction of total volume or mass, is often significantly lower than muscle found in vivo. Therefore a method to increase muscle cell density within a construct is needed. Topics: Biological tissues, Muscle |
| first_indexed | 2024-09-23T16:08:07Z |
| format | Article |
| id | mit-1721.1/118781 |
| institution | Massachusetts Institute of Technology |
| last_indexed | 2024-09-23T16:08:07Z |
| publishDate | 2018 |
| publisher | ASME International |
| record_format | dspace |
| spelling | mit-1721.1/1187812024-07-15T17:16:22Z Bioengineered Fascicle-Like Skeletal Muscle Tissue Constructs Neal, Devin M Sakar, Mahmut Selman Asada, Haruhiko Massachusetts Institute of Technology. Department of Mechanical Engineering Neal, Devin M Sakar, Mahmut Selman Asada, Haruhiko Tissue engineered skeletal muscle constructs have and will continue to be valuable in treating, and testing various muscle injuries and diseases. However a significant drawback to numerous methods of producing 3D skeletal muscle constructs grown in vitro is that muscle cell density as a fraction of total volume or mass, is often significantly lower than muscle found in vivo. Therefore a method to increase muscle cell density within a construct is needed. Topics: Biological tissues, Muscle National Science Foundation (U.S.). Center on Emergent Behaviors of Integrated Cellular Systems (Grant CBET-0939511) 2018-10-25T18:09:48Z 2018-10-25T18:09:48Z 2012-06 2018-10-23T17:39:36Z Article http://purl.org/eprint/type/ConferencePaper 978-0-7918-4480-9 http://hdl.handle.net/1721.1/118781 Neal, Devin, et al. “Bioengineered Fascicle-Like Skeletal Muscle Tissue Constructs.” ASME 2012 Summer Bioengineering Conference, Parts A and B, 20-23 June, 2012, Fajardo, Puerto Rico, ASME, 2012, p. 1133. https://orcid.org/0000-0003-3155-6223 http://dx.doi.org/10.1115/SBC2012-80228 ASME 2012 Summer Bioengineering Conference, Parts A and B Article is made available in accordance with the publisher's policy and may be subject to US copyright law. Please refer to the publisher's site for terms of use. application/pdf ASME International ASME |
| spellingShingle | Neal, Devin M Sakar, Mahmut Selman Asada, Haruhiko Bioengineered Fascicle-Like Skeletal Muscle Tissue Constructs |
| title | Bioengineered Fascicle-Like Skeletal Muscle Tissue Constructs |
| title_full | Bioengineered Fascicle-Like Skeletal Muscle Tissue Constructs |
| title_fullStr | Bioengineered Fascicle-Like Skeletal Muscle Tissue Constructs |
| title_full_unstemmed | Bioengineered Fascicle-Like Skeletal Muscle Tissue Constructs |
| title_short | Bioengineered Fascicle-Like Skeletal Muscle Tissue Constructs |
| title_sort | bioengineered fascicle like skeletal muscle tissue constructs |
| url | http://hdl.handle.net/1721.1/118781 https://orcid.org/0000-0003-3155-6223 |
| work_keys_str_mv | AT nealdevinm bioengineeredfasciclelikeskeletalmuscletissueconstructs AT sakarmahmutselman bioengineeredfasciclelikeskeletalmuscletissueconstructs AT asadaharuhiko bioengineeredfasciclelikeskeletalmuscletissueconstructs |