Integrated in vivo multiomics analysis identifies p21-activated kinase signaling as a driver of colitis

Integrated in vivo multiomics analysis identifies p21-activated kinase signaling as a driver of colitis

Inflammatory bowel disease (IBD) is a chronic disorder of the gastrointestinal tract that has limited treatment options. To gain insight into the pathogenesis of chronic colonic inflammation (colitis), we performed a multiomics analysis that integrated RNA microarray, total protein mass spectrometry...

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Detalhes bibliográficos
Principais autores: Ghazi, Phaedra C., Baldwin, Katherine R., Edwards, Amanda, Boukhali, Myriam, Lin, Yi-Jang, Yajnik, Vijay, Kissil, Joseph L., Haas, Wilhelm, Haigis, Kevin M., Lyons, Jesse Stolberg, Brubaker, Douglas, Strasser, Samantha Dale, Suarez Lopez, Lucia, Lauffenburger, Douglas A
Outros Autores: Massachusetts Institute of Technology. Department of Biological Engineering
Formato: Artigo
Idioma:en_US
Publicado em: American Association for the Advancement of Science (AAAS) 2018
Acesso em linha:http://hdl.handle.net/1721.1/118787
https://orcid.org/0000-0002-9272-4094
https://orcid.org/0000-0003-4115-5001
https://orcid.org/0000-0002-3719-0536
https://orcid.org/0000-0002-0050-989X

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