Epigenetic Modulation Using Small Molecules - Targeting Histone Acetyltransferases in Disease
Histone acetyltransferases (HATs) are epigenetic drivers that catalyze the acetyl transfer from acetyl-CoA to lysines of both histone and non-histone substrates and thereby induce transcription either by chromatin remodeling or direct transcription factor activation. Histone deacetylases (HDACs) con...
| Main Authors: | , |
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| Format: | Article |
| Language: | en_US |
| Published: |
Bentham Science
2018
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| Online Access: | http://hdl.handle.net/1721.1/118890 |