Integrated Mechanistic-Empirical Modeling of Cellular Response Based on Intracellular Signaling Dynamics
A hybrid modeling framework integrating a highly specific mechanistic model with highly abstract empirical model is presented. With the growing interest in the scientific and medical community for identification of therapeutic targets in treatment of disease, it is necessary to develop predictive mo...
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| Format: | Article |
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ASME International
2018
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| Online Access: | http://hdl.handle.net/1721.1/118971 https://orcid.org/0000-0002-9678-0157 https://orcid.org/0000-0003-3155-6223 |