Quantitative phase microscopy using deep neural networks

Deep learning has been proven to achieve ground-breaking accuracy in various tasks. In this paper, we implemented a deep neural network (DNN) to achieve phase retrieval in a wide-field microscope. Our DNN utilized the residual neural network (ResNet) architecture and was trained using the data gener...

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Bibliographic Details
Main Authors: Li, Shuai, Sinha, Ayan T, Lee, Justin, Barbastathis, George
Other Authors: Institute for Medical Engineering and Science
Format: Article
Published: SPIE 2018
Online Access:http://hdl.handle.net/1721.1/119144
https://orcid.org/0000-0002-7836-0431
https://orcid.org/0000-0002-4140-1404
Description
Summary:Deep learning has been proven to achieve ground-breaking accuracy in various tasks. In this paper, we implemented a deep neural network (DNN) to achieve phase retrieval in a wide-field microscope. Our DNN utilized the residual neural network (ResNet) architecture and was trained using the data generated by a phase SLM. The results showed that our DNN was able to reconstruct the profile of the phase target qualitatively. In the meantime, large error still existed, which indicated that our approach still need to be improved.