Helicobacter pylori CagA promotes epithelial mesenchymal transition in gastric carcinogenesis via triggering oncogenic YAP pathway

Helicobacter pylori CagA promotes epithelial mesenchymal transition in gastric carcinogenesis via triggering oncogenic YAP pathway

Background Helicobacter pylori (H. pylori) delivers oncoprotein CagA into gastric epithelial cells via the T4SS and drives activation of multiple oncogenic signalling pathways. YAP, a core effector of the Hippo tumour suppressor pathway, is frequently overexpressed in human cancers,...

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Bibliographic Details
Main Authors: Hu, Yi, He, Cong, Xie, Chuan, Ouyang, Yaobin, Huang, Deqiang, Zhu, Yin, Luo, Zhijun, Lu, Nonghua, Li, Nianshuang, Feng, Yan, Artim, Stephen, Ge, Zhongming
Other Authors: Massachusetts Institute of Technology. Division of Comparative Medicine
Format: Article
Language:English
Published: BioMed Central 2018
Online Access:http://hdl.handle.net/1721.1/119436
https://orcid.org/0000-0003-4503-9024

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