CRISPR-based genomic tools for the manipulation of genetically intractable microorganisms

Genetic manipulation of microorganisms has been crucial in understanding their biology, yet for many microbial species, robust tools for comprehensive genetic analysis were lacking until the advent of CRISPR–Cas-based gene editing techniques. In this Progress article, we discuss advances in CRISPR-b...

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Bibliographic Details
Main Authors: Chavez, Alejandro, Collins, James J., Shapiro, Rebecca
Other Authors: Massachusetts Institute of Technology. Institute for Medical Engineering & Science
Format: Article
Language:en_US
Published: Nature Publishing Group 2018
Online Access:http://hdl.handle.net/1721.1/119469
https://orcid.org/0000-0001-8167-7096
https://orcid.org/0000-0002-5560-8246

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