CRISPR-based genomic tools for the manipulation of genetically intractable microorganisms
Genetic manipulation of microorganisms has been crucial in understanding their biology, yet for many microbial species, robust tools for comprehensive genetic analysis were lacking until the advent of CRISPR–Cas-based gene editing techniques. In this Progress article, we discuss advances in CRISPR-b...
Main Authors: | Chavez, Alejandro, Collins, James J., Shapiro, Rebecca |
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Other Authors: | Massachusetts Institute of Technology. Institute for Medical Engineering & Science |
Format: | Article |
Language: | en_US |
Published: |
Nature Publishing Group
2018
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Online Access: | http://hdl.handle.net/1721.1/119469 https://orcid.org/0000-0001-8167-7096 https://orcid.org/0000-0002-5560-8246 |
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