Structurally modulated codelivery of siRNA and Argonaute 2 for enhanced RNA interference

Small interfering RNA (siRNA) represents a promising class of inhibitors in both fundamental research and the clinic. Numerous delivery vehicles have been developed to facilitate siRNA delivery. Nevertheless, achieving highly potent RNA interference (RNAi) toward clinical translation requires effici...

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Bibliographic Details
Main Authors: Elkayam, Elad, Joshua-Tor, Leemor, Li, Jiahe, Wu, Connie, Wang, Wade, He, Yanpu, Hammond, Paula T
Other Authors: Massachusetts Institute of Technology. Department of Chemical Engineering
Format: Article
Published: National Academy of Sciences (U.S.) 2018
Online Access:http://hdl.handle.net/1721.1/119482
https://orcid.org/0000-0002-4031-7286
https://orcid.org/0000-0002-7639-2122
https://orcid.org/0000-0001-9695-3604