Binding site for coenzyme A revealed in the structure of pyruvate:ferredoxin oxidoreductase from

Pyruvate:ferredoxin oxidoreductase (PFOR) is a microbial enzyme that uses thiamine pyrophosphate (TPP), three [4Fe-4S] clusters, and coenzyme A (CoA) in the reversible oxidation of pyruvate to generate acetyl-CoA and carbon dioxide. The two electrons that are generated as a result of pyruvate decarb...

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Bibliographic Details
Main Authors: Aman, Heather, Can, Mehmet, Ragsdale, Stephen W., Chen, Yang-Ting, Drennan, Catherine L
Other Authors: Massachusetts Institute of Technology. Department of Biology
Format: Article
Published: National Academy of Sciences (U.S.) 2018
Online Access:http://hdl.handle.net/1721.1/119494
https://orcid.org/0000-0001-7362-9801
https://orcid.org/0000-0001-5486-2755