Binding site for coenzyme A revealed in the structure of pyruvate:ferredoxin oxidoreductase from
Pyruvate:ferredoxin oxidoreductase (PFOR) is a microbial enzyme that uses thiamine pyrophosphate (TPP), three [4Fe-4S] clusters, and coenzyme A (CoA) in the reversible oxidation of pyruvate to generate acetyl-CoA and carbon dioxide. The two electrons that are generated as a result of pyruvate decarb...
Main Authors: | Aman, Heather, Can, Mehmet, Ragsdale, Stephen W., Chen, Yang-Ting, Drennan, Catherine L |
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Other Authors: | Massachusetts Institute of Technology. Department of Biology |
Format: | Article |
Published: |
National Academy of Sciences (U.S.)
2018
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Online Access: | http://hdl.handle.net/1721.1/119494 https://orcid.org/0000-0001-7362-9801 https://orcid.org/0000-0001-5486-2755 |
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