Matrilin-1 Is an Inhibitor of Neovascularization

In the course of conducting a series of studies whose goal was to discover novel endogenous angiogenesis inhibitors, we have purified Matrilin-1 (MATN-1) and have demonstrated, for the first time, that it inhibits neovascularization both in vitro and in vivo. Proteins were extracted from cartilage...

Full description

Bibliographic Details
Main Authors: Foradori, Matthew J., Harper, Jay, Li, Xin, Tsang, Paul C. W., Moses, Marsha A., Chen, Qian, Fernandez, Cecilia A, Langer, Robert S
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering
Format: Article
Language:en_US
Published: American Society for Biochemistry and Molecular Biology (ASBMB) 2018
Online Access:http://hdl.handle.net/1721.1/119675
https://orcid.org/0000-0002-0505-1435
https://orcid.org/0000-0003-4255-0492