Hydrogel bioelectronics
Bioelectronic interfacing with the human body including electrical stimulation and recording of neural activities is the basis of the rapidly growing field of neural science and engineering, diagnostics, therapy, and wearable and implantable devices. Owing to intrinsic dissimilarities between soft,...
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| Format: | Article |
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The Royal Society of Chemistry
2019
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| Online Access: | http://hdl.handle.net/1721.1/120165 https://orcid.org/0000-0003-1710-9750 https://orcid.org/0000-0001-5387-6186 |
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| author | Yuk, Hyunwoo Lu, Baoyang Zhao, Xuanhe |
| author2 | Massachusetts Institute of Technology. Department of Mechanical Engineering |
| author_facet | Massachusetts Institute of Technology. Department of Mechanical Engineering Yuk, Hyunwoo Lu, Baoyang Zhao, Xuanhe |
| author_sort | Yuk, Hyunwoo |
| collection | MIT |
| description | Bioelectronic interfacing with the human body including electrical stimulation and recording of neural activities is the basis of the rapidly growing field of neural science and engineering, diagnostics, therapy, and wearable and implantable devices. Owing to intrinsic dissimilarities between soft, wet, and living biological tissues and rigid, dry, and synthetic electronic systems, the development of more compatible, effective, and stable interfaces between these two different realms has been one of the most daunting challenges in science and technology. Recently, hydrogels have emerged as a promising material candidate for the next-generation bioelectronic interfaces, due to their similarities to biological tissues and versatility in electrical, mechanical, and biofunctional engineering. In this review, we discuss (i) the fundamental mechanisms of tissue-electrode interactions, (ii) hydrogels' unique advantages in bioelectrical interfacing with the human body, (iii) the recent progress in hydrogel developments for bioelectronics, and (iv) rational guidelines for the design of future hydrogel bioelectronics. Advances in hydrogel bioelectronics will usher unprecedented opportunities toward ever-close integration of biology and electronics, potentially blurring the boundary between humans and machines. |
| first_indexed | 2024-09-23T12:58:07Z |
| format | Article |
| id | mit-1721.1/120165 |
| institution | Massachusetts Institute of Technology |
| last_indexed | 2024-09-23T12:58:07Z |
| publishDate | 2019 |
| publisher | The Royal Society of Chemistry |
| record_format | dspace |
| spelling | mit-1721.1/1201652022-10-01T12:13:39Z Hydrogel bioelectronics Yuk, Hyunwoo Lu, Baoyang Zhao, Xuanhe Massachusetts Institute of Technology. Department of Mechanical Engineering Yuk, Hyunwoo Lu, Baoyang Zhao, Xuanhe Bioelectronic interfacing with the human body including electrical stimulation and recording of neural activities is the basis of the rapidly growing field of neural science and engineering, diagnostics, therapy, and wearable and implantable devices. Owing to intrinsic dissimilarities between soft, wet, and living biological tissues and rigid, dry, and synthetic electronic systems, the development of more compatible, effective, and stable interfaces between these two different realms has been one of the most daunting challenges in science and technology. Recently, hydrogels have emerged as a promising material candidate for the next-generation bioelectronic interfaces, due to their similarities to biological tissues and versatility in electrical, mechanical, and biofunctional engineering. In this review, we discuss (i) the fundamental mechanisms of tissue-electrode interactions, (ii) hydrogels' unique advantages in bioelectrical interfacing with the human body, (iii) the recent progress in hydrogel developments for bioelectronics, and (iv) rational guidelines for the design of future hydrogel bioelectronics. Advances in hydrogel bioelectronics will usher unprecedented opportunities toward ever-close integration of biology and electronics, potentially blurring the boundary between humans and machines. National Science Foundation (U.S.) (CMMI-1661627) United States. Office of Naval Research (N00014-17-1-2920) Massachusetts Institute of Technology. Institute for Soldier Nanotechnologies (W911NF-13-D-0001) Samsung Scholarship Foundation National Natural Science Foundation (China) (51763010) Science Foundation for Excellent Youth Talents in Jiangxi Province (20162BCB23053) Key Research and Development Program of Jiangxi Province (20171BBH80007) Natural Science Foundation of Jiangxi Province (20171BAB216018) China Scholarship Council (201608360062) 2019-02-04T15:21:40Z 2019-02-04T15:21:40Z 2018-11 2018-07 2019-01-16T14:22:29Z Article http://purl.org/eprint/type/JournalArticle 0306-0012 1460-4744 http://hdl.handle.net/1721.1/120165 Yuk, Hyunwoo, Baoyang Lu, and Xuanhe Zhao. “Hydrogel Bioelectronics.” Chemical Society Reviews (November 2019). © 2018 The Royal Society of Chemistry https://orcid.org/0000-0003-1710-9750 https://orcid.org/0000-0001-5387-6186 http://dx.doi.org/10.1039/c8cs00595h Chemical Society Reviews Creative Commons Attribution Noncommercial 3.0 unported license https://creativecommons.org/licenses/by-nc/3.0/ application/pdf The Royal Society of Chemistry Royal Society of Chemistry (RSC) |
| spellingShingle | Yuk, Hyunwoo Lu, Baoyang Zhao, Xuanhe Hydrogel bioelectronics |
| title | Hydrogel bioelectronics |
| title_full | Hydrogel bioelectronics |
| title_fullStr | Hydrogel bioelectronics |
| title_full_unstemmed | Hydrogel bioelectronics |
| title_short | Hydrogel bioelectronics |
| title_sort | hydrogel bioelectronics |
| url | http://hdl.handle.net/1721.1/120165 https://orcid.org/0000-0003-1710-9750 https://orcid.org/0000-0001-5387-6186 |
| work_keys_str_mv | AT yukhyunwoo hydrogelbioelectronics AT lubaoyang hydrogelbioelectronics AT zhaoxuanhe hydrogelbioelectronics |