Health selection into neighborhoods among patients enrolled in a clinical trial
Health selection into neighborhoods may contribute to geographic health disparities. We demonstrate the potential for clinical trial data to help clarify the causal role of health on locational attainment. We used data from the 20-year United Kingdom Prospective Diabetes Study (UKPDS) to explore whe...
| Main Authors: | , , , , |
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| Other Authors: | |
| Format: | Article |
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Elsevier BV
2019
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| Online Access: | http://hdl.handle.net/1721.1/120182 https://orcid.org/0000-0001-8095-0249 |
| _version_ | 1811079230979571712 |
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| author | Coleman, Ruth L. Razak, Fahad Holman, Rury R. Arcaya, Mariana Clair Alvarez, Mariajose |
| author2 | Massachusetts Institute of Technology. Department of Urban Studies and Planning |
| author_facet | Massachusetts Institute of Technology. Department of Urban Studies and Planning Coleman, Ruth L. Razak, Fahad Holman, Rury R. Arcaya, Mariana Clair Alvarez, Mariajose |
| author_sort | Coleman, Ruth L. |
| collection | MIT |
| description | Health selection into neighborhoods may contribute to geographic health disparities. We demonstrate the potential for clinical trial data to help clarify the causal role of health on locational attainment. We used data from the 20-year United Kingdom Prospective Diabetes Study (UKPDS) to explore whether random assignment to intensive blood-glucose control therapy, which improved long-term health outcomes after median 10 years follow-up, subsequently affected what neighborhoods patients lived in. We extracted postcode-level deprivation indices for the 2710 surviving participants of UKPDS living in England at study end in 1996/1997. We observed small neighborhood advantages in the intensive versus conventional therapy group, although these differences were not statistically significant. This analysis failed to show conclusive evidence of health selection into neighborhoods, but data suggest the hypothesis may be worthy of exploration in other clinical trials or in a meta-analysis. Keywords:
Neighborhoods, Self-selection, Health, Equity, Socioeconomic status |
| first_indexed | 2024-09-23T11:11:55Z |
| format | Article |
| id | mit-1721.1/120182 |
| institution | Massachusetts Institute of Technology |
| last_indexed | 2024-09-23T11:11:55Z |
| publishDate | 2019 |
| publisher | Elsevier BV |
| record_format | dspace |
| spelling | mit-1721.1/1201822022-09-27T17:46:46Z Health selection into neighborhoods among patients enrolled in a clinical trial Coleman, Ruth L. Razak, Fahad Holman, Rury R. Arcaya, Mariana Clair Alvarez, Mariajose Massachusetts Institute of Technology. Department of Urban Studies and Planning Arcaya, Mariana Clair Alvarez, Mariajose Health selection into neighborhoods may contribute to geographic health disparities. We demonstrate the potential for clinical trial data to help clarify the causal role of health on locational attainment. We used data from the 20-year United Kingdom Prospective Diabetes Study (UKPDS) to explore whether random assignment to intensive blood-glucose control therapy, which improved long-term health outcomes after median 10 years follow-up, subsequently affected what neighborhoods patients lived in. We extracted postcode-level deprivation indices for the 2710 surviving participants of UKPDS living in England at study end in 1996/1997. We observed small neighborhood advantages in the intensive versus conventional therapy group, although these differences were not statistically significant. This analysis failed to show conclusive evidence of health selection into neighborhoods, but data suggest the hypothesis may be worthy of exploration in other clinical trials or in a meta-analysis. Keywords: Neighborhoods, Self-selection, Health, Equity, Socioeconomic status 2019-02-04T19:48:16Z 2019-02-04T19:48:16Z 2017-12 2017-07 2019-01-16T17:03:57Z Article http://purl.org/eprint/type/JournalArticle 2211-3355 http://hdl.handle.net/1721.1/120182 Arcaya, Mariana C., Ruth L. Coleman, Fahad Razak, Maria L. Alva, and Rury R. Holman. “Health Selection into Neighborhoods Among Patients Enrolled in a Clinical Trial.” Preventive Medicine Reports 8 (December 2017): 51–54. © 2017 The Authors https://orcid.org/0000-0001-8095-0249 http://dx.doi.org/10.1016/J.PMEDR.2017.07.003 Preventive Medicine Reports Creative Commons Attribution-NonCommercial-NoDerivs License http://creativecommons.org/licenses/by-nc-nd/4.0/ application/pdf Elsevier BV Elsevier |
| spellingShingle | Coleman, Ruth L. Razak, Fahad Holman, Rury R. Arcaya, Mariana Clair Alvarez, Mariajose Health selection into neighborhoods among patients enrolled in a clinical trial |
| title | Health selection into neighborhoods among patients enrolled in a clinical trial |
| title_full | Health selection into neighborhoods among patients enrolled in a clinical trial |
| title_fullStr | Health selection into neighborhoods among patients enrolled in a clinical trial |
| title_full_unstemmed | Health selection into neighborhoods among patients enrolled in a clinical trial |
| title_short | Health selection into neighborhoods among patients enrolled in a clinical trial |
| title_sort | health selection into neighborhoods among patients enrolled in a clinical trial |
| url | http://hdl.handle.net/1721.1/120182 https://orcid.org/0000-0001-8095-0249 |
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