Enhancing Humoral Responses Against HIV Envelope Trimers via Nanoparticle Delivery with Stabilized Synthetic Liposomes

Enhancing Humoral Responses Against HIV Envelope Trimers via Nanoparticle Delivery with Stabilized Synthetic Liposomes

An HIV vaccine capable of eliciting durable neutralizing antibody responses continues to be an important unmet need. Multivalent nanoparticles displaying a high density of envelope trimers may be promising immunogen forms to elicit strong and durable humoral responses to HIV, but critical particle d...

Full description

Bibliographic Details
Main Authors: Kulp, Daniel W., Mutafyan, Andrew A., Jones, Christopher A., Menis, Sergey, Georgeson, Erik, Kubitz, Mike, Zhang, Michael H., Melo, Mariane B., Silva, Murillo, Yun, Dong Soo, Schief, William R., Tokatlian, Talar, Irvine, Darrell J
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering
Format: Article
Published: Nature Publishing Group 2019
Online Access:http://hdl.handle.net/1721.1/120844
https://orcid.org/0000-0001-8452-6752

Similar Items

Similar Items