Summary: | Purpose—To report on a posterior segment coloboma manifesting unusual morphology as
determined by high-speed, ultrahigh resolution optical coherence tomography imaging (hsUHROCT).
Methods—A 47-year-old patient with bilateral colobomas was evaluated via fundus examination
and hsUHR-OCT.
Results—Imaging with hsUHR-OCT showed intact retinal pigment epithelium (RPE) within the
posterior segment coloboma. Most of the retinal layers appeared to continue into the coloboma,
although they exhibited slight attenuation. The external limiting membrane (ELM) was clearly
visible continuing within the coloboma, suggesting that Muller cells and the inner segments of the
photoreceptors were still present in this area. The junction between the inner and outer segments
of the photoreceptors ended at the margin of the coloboma, which may be due to either
photoreceptor disruption or a change in the orientation of the outer segments.
Conclusion—hsUHR-OCT demonstrated the presence of Muller cells and photoreceptor inner
segments within a posterior segment coloboma. The retinal pigment epithelium (RPE) was intact
within the coloboma, representing an unusual morphology.
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