Directing curli polymerization with DNA origami nucleators

Directing curli polymerization with DNA origami nucleators

The physiological or pathological formation of fibrils often relies on molecular-scale nucleators that finely control the kinetics and structural features. However, mechanistic understanding of how protein nucleators mediate fibril formation in cells remains elusive. Here, we develop a CsgB-decorate...

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Bibliographic Details
Main Authors: Mao, Xiuhai, Li, Ke, Liu, Mengmeng, Wang, Xinyu, Zhao, Tianxin, An, Bolin, Cui, Mengkui, Li, Yingfeng, Pu, Jiahua, Li, Jiang, Wang, Lihua, Lu, Timothy K, Fan, Chunhai, Zhong, Chao
Other Authors: Massachusetts Institute of Technology. Synthetic Biology Center
Format: Article
Language:English
Published: Nature Publishing Group 2019
Online Access:https://hdl.handle.net/1721.1/121274

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