Optical Coherence Tomography Angiography of Dry Age-Related Macular Degeneration
Optical coherence tomography angiography (OCTA) can be used to visualize alterations in the choriocapillaris of patients with dry age-related macular degeneration (AMD). These changes seem to be present during all stages of the disease. Earlier stages are associated with patchy thinning of the chori...
| Main Authors: | , , , |
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| Other Authors: | |
| Format: | Book |
| Language: | English |
| Published: |
S. Karger AG
2019
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| Online Access: | https://hdl.handle.net/1721.1/121578 |
| _version_ | 1811073478749585408 |
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| author | Waheed, Nadia K. Moult, Eric Michael Fujimoto, James G Rosenfeld, Philip J. |
| author2 | Massachusetts Institute of Technology. Department of Electrical Engineering and Computer Science |
| author_facet | Massachusetts Institute of Technology. Department of Electrical Engineering and Computer Science Waheed, Nadia K. Moult, Eric Michael Fujimoto, James G Rosenfeld, Philip J. |
| author_sort | Waheed, Nadia K. |
| collection | MIT |
| description | Optical coherence tomography angiography (OCTA) can be used to visualize alterations in the choriocapillaris of patients with dry age-related macular degeneration (AMD). These changes seem to be present during all stages of the disease. Earlier stages are associated with patchy thinning of the choriocapillaris, while geographic atrophy is associated with loss of choriocapillaris lying under the area of geographic atrophy and asymmetric alteration of choriocapillaris at the margins of the geographic atrophy. The use of high-speed, long-wave-length swept-source OCT for angiography, with its better penetration into the choroid and high acquisition speeds, enable OCTA with scaled slowest detectable flow and fastest distinguishable flow. This will enable us to better investigate choriocapillaris changes in patients with dry AMD. The ability to image the choriocapillaris structure and flow impairments may be useful in the future for detecting and monitoring the progression of dry AMD and for monitoring treatment responses in clinical trials to therapies that target disease progression in dry AMD. |
| first_indexed | 2024-09-23T09:33:45Z |
| format | Book |
| id | mit-1721.1/121578 |
| institution | Massachusetts Institute of Technology |
| language | English |
| last_indexed | 2024-09-23T09:33:45Z |
| publishDate | 2019 |
| publisher | S. Karger AG |
| record_format | dspace |
| spelling | mit-1721.1/1215782022-09-30T15:18:49Z Optical Coherence Tomography Angiography of Dry Age-Related Macular Degeneration Waheed, Nadia K. Moult, Eric Michael Fujimoto, James G Rosenfeld, Philip J. Massachusetts Institute of Technology. Department of Electrical Engineering and Computer Science Massachusetts Institute of Technology. Research Laboratory of Electronics Massachusetts Institute of Technology. Institute for Medical Engineering & Science Optical coherence tomography angiography (OCTA) can be used to visualize alterations in the choriocapillaris of patients with dry age-related macular degeneration (AMD). These changes seem to be present during all stages of the disease. Earlier stages are associated with patchy thinning of the choriocapillaris, while geographic atrophy is associated with loss of choriocapillaris lying under the area of geographic atrophy and asymmetric alteration of choriocapillaris at the margins of the geographic atrophy. The use of high-speed, long-wave-length swept-source OCT for angiography, with its better penetration into the choroid and high acquisition speeds, enable OCTA with scaled slowest detectable flow and fastest distinguishable flow. This will enable us to better investigate choriocapillaris changes in patients with dry AMD. The ability to image the choriocapillaris structure and flow impairments may be useful in the future for detecting and monitoring the progression of dry AMD and for monitoring treatment responses in clinical trials to therapies that target disease progression in dry AMD. 2019-07-10T18:35:24Z 2019-07-10T18:35:24Z 2016 2019-06-21T18:06:48Z Book http://purl.org/eprint/type/JournalArticle 9783318058291 9783318058307 0250-3751 1662-2790 https://hdl.handle.net/1721.1/121578 Waheed, N. K. et al. "Optical Coherence Tomography Angiography of Dry Age-Related Macular Degeneration et al." OCT Angiography in Retinal and Macular Diseases 56 (2016): 91-100 © 2016 S. Karger AG en http://dx.doi.org/10.1159/000442784 OCT Angiography in Retinal and Macular Diseases Creative Commons Attribution-Noncommercial-Share Alike http://creativecommons.org/licenses/by-nc-sa/4.0/ application/pdf S. Karger AG PMC |
| spellingShingle | Waheed, Nadia K. Moult, Eric Michael Fujimoto, James G Rosenfeld, Philip J. Optical Coherence Tomography Angiography of Dry Age-Related Macular Degeneration |
| title | Optical Coherence Tomography Angiography of Dry Age-Related Macular Degeneration |
| title_full | Optical Coherence Tomography Angiography of Dry Age-Related Macular Degeneration |
| title_fullStr | Optical Coherence Tomography Angiography of Dry Age-Related Macular Degeneration |
| title_full_unstemmed | Optical Coherence Tomography Angiography of Dry Age-Related Macular Degeneration |
| title_short | Optical Coherence Tomography Angiography of Dry Age-Related Macular Degeneration |
| title_sort | optical coherence tomography angiography of dry age related macular degeneration |
| url | https://hdl.handle.net/1721.1/121578 |
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