Poly(glycoamidoamine) brush nanomaterials for systemic siRNA delivery in vivo
Delivery is the key challenge for siRNA based therapeutics. Here, we report the development of new poly(glycoamidoamine) brush nanomaterials for efficient siRNA delivery. GluN4C10 polymer brush nanoparticles, a lead material, demonstrated significantly improved delivery efficiency for siRNA against...
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Bibliographic Details
| Main Authors: |
Luo, X.,
Wang, Wei,
Dorkin, Joseph Robert,
Veiseh, Omid,
Chang, Pyung-Hun,
Abutbul-Ionita, I.,
Danino, D.,
Langer, Robert S,
Anderson, Daniel Griffith,
Dong, Y. |
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| Other Authors: |
Massachusetts Institute of Technology. Department of Biology |
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| Format: | Article
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| Language: | English |
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| Published: |
Royal Society of Chemistry (RSC)
2019
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| Online Access: | https://hdl.handle.net/1721.1/121985
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