Simultaneous spatiotemporal tracking and oxygen sensing of transient implants in vivo using hot-spot MRI and machine learning
A varying oxygen environment is known to affect cellular function in disease as well as activity of various therapeutics. For transient structures, whether they are unconstrained therapeutic transplants, migrating cells during tumor metastasis, or cell populations induced by an immunological respons...
Main Authors: | Spanoudaki, Virginia, Doloff, Joshua C, Huang, Wei, Norcross, Samuel, Farah, Shady, Langer, Robert S, Anderson, Daniel Griffith |
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Other Authors: | Massachusetts Institute of Technology. Department of Chemical Engineering |
Format: | Article |
Language: | English |
Published: |
Proceedings of the National Academy of Sciences
2019
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Online Access: | https://hdl.handle.net/1721.1/122032 |
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