Porting the synthetic D-glucaric acid pathway fromEscherichia colito Saccharomyces cerevisiae

D-Glucaric acid can be produced as a value-added chemical from biomass through a de novo pathway in Escherichia coli. However, previous studies have identified pH-mediated toxicity at product concentrations of 5 g/L and have also found the eukaryotic myo-inositol oxygenase (MIOX) enzyme to be rate-l...

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Bibliographic Details
Main Authors: Gupta, Amita, Hicks, Michael A., Manchester, Shawn, Prather, Kristala L
Other Authors: Massachusetts Institute of Technology. Department of Chemical Engineering
Format: Article
Language:English
Published: Wiley 2019
Online Access:https://hdl.handle.net/1721.1/122605