Dissecting the complex landscape of neuroinflammation at single-cell resolution
A new study, using a mouse model of multiple sclerosis, applied single-cell RNA sequencing to determine how immune cells in the CNS respond during inflammation. In addition to highlighting novel subtypes of cells that evolve over the course of disease, the findings have important implications for de...
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| Format: | Article |
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Springer Science and Business Media LLC
2019
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| Online Access: | https://hdl.handle.net/1721.1/122946 |
| _version_ | 1826201120905625600 |
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| author | Raju, Ravikiran M. Tsai, Li-Huei |
| author2 | Picower Institute for Learning and Memory |
| author_facet | Picower Institute for Learning and Memory Raju, Ravikiran M. Tsai, Li-Huei |
| author_sort | Raju, Ravikiran M. |
| collection | MIT |
| description | A new study, using a mouse model of multiple sclerosis, applied single-cell RNA sequencing to determine how immune cells in the CNS respond during inflammation. In addition to highlighting novel subtypes of cells that evolve over the course of disease, the findings have important implications for developing targeted therapies for inflammatory demyelinating diseases. Keyword: brain; experimental models of disease; multiple sclerosis |
| first_indexed | 2024-09-23T11:46:52Z |
| format | Article |
| id | mit-1721.1/122946 |
| institution | Massachusetts Institute of Technology |
| last_indexed | 2024-09-23T11:46:52Z |
| publishDate | 2019 |
| publisher | Springer Science and Business Media LLC |
| record_format | dspace |
| spelling | mit-1721.1/1229462022-09-27T21:51:29Z Dissecting the complex landscape of neuroinflammation at single-cell resolution The complexity of neuroinflammation at single-cell resolution Raju, Ravikiran M. Tsai, Li-Huei Picower Institute for Learning and Memory A new study, using a mouse model of multiple sclerosis, applied single-cell RNA sequencing to determine how immune cells in the CNS respond during inflammation. In addition to highlighting novel subtypes of cells that evolve over the course of disease, the findings have important implications for developing targeted therapies for inflammatory demyelinating diseases. Keyword: brain; experimental models of disease; multiple sclerosis 2019-11-15T15:48:17Z 2019-11-15T15:48:17Z 2019-03 Article http://purl.org/eprint/type/JournalArticle 1759-4758 1759-4766 https://hdl.handle.net/1721.1/122946 Raju, Ravikiran M., and Li-Huei Tsai. "The complexity of neuroinflammation at single-cell resolution." Nature Reviews Neurology 15, 5 (May 2019): 249–250 © 2019 Springer Nature Limited http://dx.doi.org/10.1103/10.1038/s41582-019-0165-5 Nature Reviews Neurology Creative Commons Attribution-Noncommercial-Share Alike http://creativecommons.org/licenses/by-nc-sa/4.0/ application/vnd.openxmlformats-officedocument.wordprocessingml.document application/pdf Springer Science and Business Media LLC Prof. Tsai via Courtney Crummett |
| spellingShingle | Raju, Ravikiran M. Tsai, Li-Huei Dissecting the complex landscape of neuroinflammation at single-cell resolution |
| title | Dissecting the complex landscape of neuroinflammation at single-cell resolution |
| title_full | Dissecting the complex landscape of neuroinflammation at single-cell resolution |
| title_fullStr | Dissecting the complex landscape of neuroinflammation at single-cell resolution |
| title_full_unstemmed | Dissecting the complex landscape of neuroinflammation at single-cell resolution |
| title_short | Dissecting the complex landscape of neuroinflammation at single-cell resolution |
| title_sort | dissecting the complex landscape of neuroinflammation at single cell resolution |
| url | https://hdl.handle.net/1721.1/122946 |
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